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  • Publication
    Timely ICU Outcome Prediction Utilizing Stochastic Signal Analysis and Machine Learning Techniques with Readily Available Vital Sign Data
    (IEEE Journal of Biomedical and Health Informatics, 2024-06-18) Wang, Shaodong ; Jiang, Yiqun ; Li, Qing ; Zhang, Wenli ; Industrial and Manufacturing Systems Engineering ; Information Systems and Business Analytics
    The ICU is a specialized hospital department that offers critical care to patients at high risk. The massive burden of ICU-requiring care requires accurate and timely ICU outcome predictions for alleviating the economic and healthcare burdens imposed by critical care needs. Existing research faces challenges such as feature extraction difficulties, low accuracy, and resource-intensive features. Some studies have explored deep learning models that utilize raw clinical inputs. However, these models are considered non-interpretable black boxes, which prevents their wide application. The objective of the study is to develop a new method using stochastic signal analysis and machine learning techniques to effectively extract features with strong predictive power from ICU patients' real-time time series of vital signs for accurate and timely ICU outcome prediction. The results show the proposed method extracted meaningful features and outperforms baseline methods, including APACHE IV (AUC = 0.750), deep learning-based models (AUC = 0.732, 0.712, 0.698, 0.722), and statistical feature classification methods (AUC = 0.765) by a large margin (AUC = 0.869). The proposed method has clinical, management, and administrative implications since it enables healthcare professionals to identify deviations from prognostications timely and accurately and, therefore, to conduct proper interventions.
  • Publication
    On the return of the Biennial Conference on Chemical Education
    (American Chemical Society and Division of Chemical Education, Inc., 2022-09-13) Holme, Thomas ; Chemistry
    After a four year hiatus, caused by the challenges of the pandemic, the ACS Division of Chemical Education held the 27th Biennial Conference on Chemical Education at Purdue University as an in-person conference. With all the complexity of the ongoing presence of SARS-CoV-2, there were many possible ways to think about and process the experiences associated with this conference. Capturing the moment and pondering its impact may allow chemistry educators to think about how scientific conferences can best meet the needs of the communities they serve, today and into the future.
  • Publication
    The Tapestry of Chemistry Education
    (American Chemical Society and Division of Chemical Education, Inc., 2022-10-11) Holme, Thomas ; Chemistry
    Academic journals, including the Journal of Chemical Education, are repositories of individual works from communities of scholars. Often the use of information from journals is discrete, operating at the level of the individual article. Indeed, the use of search engines and rapid electronic delivery of individual articles as a PDF file has likely exacerbated this tendency. For chemistry education, National Chemistry Week presents an opportunity to contemplate the larger picture, woven as if a tapestry, for the teaching and learning of chemistry. Even a brief synopsis of a small fraction of articles in this Journal shows that taking such a broad point of view reveals a field that is constantly creating a dynamic pathway for students to find their favorite piece of the picture of chemistry.
  • Publication
    A century of a passion for teaching and learning chemistry
    (American Chemical Society, 2023-12-12) Holme, Thomas ; Chemistry
    The efforts to look at the past century of teaching chemistry in celebration of the Journal of Chemical Education’s milestone of publishing its 100th volume are reviewed. The conclusion of volume 100 allows the examination of this delightful, but challenging, year-long task of how to exemplify 100 years of teaching innovations that have touched every subdiscipline of chemistry. Looking at the rich trajectory of improvement in teaching and learning of chemical sciences strongly suggests that the second century of the Journal of Chemical Education will be as dynamic, creative, accomplished, and relevant as the first 100 years.
  • Publication
    Finish at the Beginning: 100 Years of High School Chemical Education
    (American Chemical Society, 2023-11-14) Holme, Thomas ; Chemistry
    Articles in the virtual issue about teaching and learning chemistry in high school that have appeared in the Journal over the past 100 volumes are summarized. The role of the Journal in fostering discussion of the chemistry content that comprises the high school curriculum is noted, along with changes in pedagogical approaches that have emerged over the years. Several specific articles serve as examples within this editorial, and the entire virtual issue can be accessed at this link: https://pubs.acs.org/page/jceda8/vi/JCE100yr-HSC.