Facile Synthesis of Multivalent Water-Soluble Organic Nanoparticles via “Surface Clicking” of Alkynylated Surfactant Micelles

Thumbnail Image
Supplemental Files
Date
2010-04-01
Authors
Zhang, Shiyong
Major Professor
Advisor
Committee Member
Journal Title
Journal ISSN
Volume Title
Publisher
Authors
Person
Zhao, Yan
Professor
Research Projects
Organizational Units
Organizational Unit
Chemistry

The Department of Chemistry seeks to provide students with a foundation in the fundamentals and application of chemical theories and processes of the lab. Thus prepared they me pursue careers as teachers, industry supervisors, or research chemists in a variety of domains (governmental, academic, etc).

History
The Department of Chemistry was founded in 1880.

Dates of Existence
1880-present

Related Units

Journal Issue
Is Version Of
Versions
Series
Department
Abstract

Multivalent interactions occur frequently between biological entities.1 When strong binding is not achievable with a single receptor-ligand pair, multivalency, or simultaneous binding between multiple receptors and ligands, becomes an effective strategy to enhance the binding. Significant efforts have been devoted in recent years to synthetic multivalent ligands and their interactions with biological hosts.2 Two of the most widely used scaffolds in multivalency are dendrimers and gold nanoparticles protected with functionalized thiols.

Comments

Reprinted (adapted) with permission from Macromolecules 43 (2010): 4020, doi:10.1021/ma100497k. Copyright 2010 American Chemical Society.

Description
Keywords
Citation
DOI
Subject Categories
Copyright
Fri Jan 01 00:00:00 UTC 2010
Collections