Nutritional Effects on the Gut Microbiome & the Brain-Gut Axis: Unlocking the Therapeutic and Preventative Potential of Nutrition for Gut Dysbiosis Associated Diseases

dc.contributor.author Freund, Sarah
dc.contributor.author Allenspatch, Karin
dc.contributor.author Mochel, Jonathan
dc.contributor.author Mochel, Jonathan
dc.contributor.department Biomedical Sciences
dc.contributor.department Veterinary Diagnostic and Production Animal Medicine
dc.contributor.department Veterinary Diagnostic Laboratory
dc.date 2021-05-21T17:05:50.000
dc.date.accessioned 2021-08-14T02:23:05Z
dc.date.available 2021-08-14T02:23:05Z
dc.date.copyright Fri Jan 01 00:00:00 UTC 2021
dc.date.issued 2021-05-13
dc.description.abstract <p>Diet plays a pivotal role in the overall health of an individual. Not only does it help carry out and regulate certain physiological functions, but it also can determine the composition of the gut microbiome. While the relative number of microorganisms that make up the gut microbiome vary between individuals and can be dependent on different environmental factors, there is evidence to suggest that composition of the microbiome can correlate with overall health or disease. When the GI microbiome is disturbed or suddenly changes it results in microbiome dysbiosis, a condition that correlates with the presence of certain diseases. Diseases linked to microbiome dysbiosis range from metabolic disorders, inflammatory bowel diseases to disorders of the brain. Many of these diseases are linked to the connection between the brain and the gut, known as the brain-gut axis. This bidirectional communication is important to maintain normal intestinal function, but is also responsible for the GI response to emotions as well as the emotional response to GI disturbances. By exploiting the interaction between microbiome health and nutrition, diet can be used to alleviate disease symptoms, protect against the development of certain conditions, and better maintain overall health. This review will examine the effects of nutrition on the microbiome, diseases linked to disruption of the normal microbiome, and the way that altering the diet can mitigate symptoms or prevent disease.</p>
dc.description.comments <p>This is a pre-print of the article Freund, Sarah, Jonathan Mochel, and Karin Allenspatch. "Nutritional Effects on the Gut Microbiome & the Brain-Gut Axis: Unlocking the Therapeutic and Preventative Potential of Nutrition for Gut Dysbiosis Associated Diseases." <em>Preprints</em> (2021). Posted with permission.</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/bms_pubs/100/
dc.identifier.articleid 1099
dc.identifier.contextkey 23028599
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath bms_pubs/100
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/NveoaxOz
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/bms_pubs/100/2021_MochelJonathan_NutritionalEffects.pdf|||Fri Jan 14 18:12:01 UTC 2022
dc.subject.disciplines Biochemistry
dc.subject.disciplines Veterinary Pathology and Pathobiology
dc.subject.disciplines Veterinary Preventive Medicine, Epidemiology, and Public Health
dc.subject.keywords Gut-Brain Axis
dc.subject.keywords Nutrition
dc.subject.keywords Microbiome
dc.subject.keywords SCFA
dc.subject.keywords Gut dysbiosis
dc.title Nutritional Effects on the Gut Microbiome & the Brain-Gut Axis: Unlocking the Therapeutic and Preventative Potential of Nutrition for Gut Dysbiosis Associated Diseases
dc.type article
dc.type.genre article
dspace.entity.type Publication
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relation.isOrgUnitOfPublication 5ab07352-4171-4f53-bbd7-ac5d616f7aa8
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