The new genetic environment of cfr on plasmid pBS-02 in a Bacillus strain

dc.contributor.author Zhang, Wan-Jiang
dc.contributor.author Wu, Cong-Ming
dc.contributor.author Wang, Yang
dc.contributor.author Shen, Zhang-Qi
dc.contributor.author Dai, Lei
dc.contributor.author Han, Jing
dc.contributor.author Foley, Steven
dc.contributor.author Shen, Jian-Zhong
dc.contributor.author Zhang, Qijing
dc.contributor.department Veterinary Microbiology and Preventive Medicine
dc.date 2018-02-18T23:06:50.000
dc.date.accessioned 2020-07-07T05:14:35Z
dc.date.available 2020-07-07T05:14:35Z
dc.date.issued 2011-05-01
dc.description.abstract <p>Sir,</p> <p>The gene <em>cfr</em>, encoding a 23S rRNA methyltransferase, confers resistance to five chemically unrelated antimicrobial classes, including phenicols, lincosamides, oxazolidinones, pleuromutilins and streptogramin A (PhLOPS<sub>A</sub>), and has been observed mainly in staphylococcal isolates over the past decade.<sup><a>1–3</a></sup> Our previous study reported a <em>cfr</em>-carrying plasmid, pBS-01, in a novel strain (BS-01) of a <em>Bacillus</em> species isolated from a pig farm in China.<sup><a>4</a></sup> In our routine surveillance study on antimicrobial resistance in farm animals in 2010, another florfenicol and chloramphenicol-resistant <em>Bacillus</em> species strain (named BS-02) from swine faeces was identified. Gram staining, sequence analysis of the 16S rRNA and API 50CH testing associated with the API 20E system (bioMérieux, France) showed that BS-02 had an identical profile to that of strain BS-01, which suggested that BS-02 also belongs to a novel <em>Bacillus</em> species. Despite their identical profiles, more than six PFGE band differences were observed between BS-01 and BS-02 (data not shown), indicating that they belong to different clonal types of the same species.</p>
dc.description.comments <p>This article is published as Zhang, Wan-Jiang, Cong-Ming Wu, Yang Wang, Zhang-Qi Shen, Lei Dai, Jing Han, Steven L. Foley, Jian-Zhong Shen, and Qijing Zhang. "The new genetic environment of cfr on plasmid pBS-02 in a Bacillus strain." Journal of antimicrobial chemotherapy 66, no. 5 (2011): 1174-1175. doi: <a href="https://doi.org/10.1093/jac/dkr037">10.1093/jac/dkr037</a>. Posted with permission.</p>
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dc.identifier archive/lib.dr.iastate.edu/vmpm_pubs/145/
dc.identifier.articleid 1145
dc.identifier.contextkey 10786314
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath vmpm_pubs/145
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/92249
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/vmpm_pubs/145/2011_Zhang_NewGenetic.pdf|||Fri Jan 14 20:21:21 UTC 2022
dc.source.uri 10.1093/jac/dkr037
dc.subject.disciplines Genetics and Genomics
dc.subject.disciplines Veterinary Microbiology and Immunobiology
dc.subject.disciplines Veterinary Pathology and Pathobiology
dc.subject.disciplines Veterinary Preventive Medicine, Epidemiology, and Public Health
dc.subject.keywords florfenicol resistance
dc.subject.keywords IS256
dc.subject.keywords restriction-modification system
dc.title The new genetic environment of cfr on plasmid pBS-02 in a Bacillus strain
dc.type article
dc.type.genre article
dspace.entity.type Publication
relation.isAuthorOfPublication 1c6a5dfc-c604-457f-85be-122910db782e
relation.isOrgUnitOfPublication 16f8e472-b1cd-4d8f-b016-09e96dbc4d83
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