Assessment of the diagnostic accuracy of three commercial ELISAs for the detection of antibodies against Salmonella spp in pigs through Bayesian methods
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The SafePork conference series began in 1996 to bring together international researchers, industry, and government agencies to discuss current Salmonella research and identify research needs pertaining to both pig and pork production. In subsequent years topics of research presented at these conferences expanded to include other chemical and biological hazards to pig and pork production.
The diagnostic accuracy of three ELISA tests (Herdcheck® Swine Salmonella, SALMOTYPE® Pig Screen, and PrioCHECK® Salmonella) was analysed. A low correlation between herd prevalence according to bacteriology and herd seroprevalence using the three ELISAs was found. Their estimated sensitivity (Se) and specificity (Sp) using a Bayesian approach was variable, with Herdcheck® Swine Salmonella showing the best overall accuracy (Se= 0.88; Sp= 0.74). All of the ELISAs overlooked an important proportion of Salmonella-infected pigs.