Genetic and genomic characterization of vulva size traits in Yorkshire and Landrace gilts

Date
2020-03-12
Authors
Corredor, Flor-Anita
Sanglard, Leticia
Leach, Richard
Keating, Aileen
Ross, Jason
Keating, Aileen
Serão, Nick
Journal Title
Journal ISSN
Volume Title
Publisher
Altmetrics
Authors
Research Projects
Organizational Units
Animal Science
Organizational Unit
Iowa Pork Industry Center
Organizational Unit
Journal Issue
Series
Abstract

Background: Reproductive performance is critical for efficient swine production. Recent results indicated that vulva size (VS) may be predictive of reproductive performance in sows. Study objectives were to estimate genetic parameters, identify genomic regions associated, and estimate genomic prediction accuracies (GPA) for VS traits.

Results: Heritability estimates of VS traits, vulva area (VA), height (VH), and width (VW) measurements, were moderately to highly heritable in Yorkshire, with 0.46 ± 0.10, 0.55 ± 0.10, 0.31 ± 0.09, respectively, whereas these estimates were low to moderate in Landrace, with 0.16 ± 0.09, 0.24 ± 0.11, and 0.08 ± 0.06, respectively. Genetic correlations within VS traits were very high for both breeds, with the lowest of 0.67 ± 0.29 for VH and VW for Landrace. Genome-wide association studies (GWAS) for Landrace, reveled genomic region associated with VS traits on Sus scrofa chromosome (SSC) 2 (154–157Mb), 7 (107–110 Mb), 8 (4–6Mb), and 10 (8–19 Mb). For Yorkshire, genomic regions on SSC 1 (87–91 and 282–287Mb) and 5 (67Mb) were identified. All regions explained at least 3.4% of the genetic variance. Accuracies of genomic prediction were moderate in Landrace, ranging from 0.30 (VH) to 0.61 (VA), and lower for Yorkshire, with 0.07 (VW) to 0.11 (VH). Between-breed and multi-breed genomic prediction accuracies were low.

Conclusions: Our findings suggest that VS traits are heritable in Landrace and Yorkshire gilts. Genomic analyses show that major QTL control these traits, and they differ between breed. Genomic information can be used to increase genetic gains for these traits in gilts. Additional research must be done to validate the GWAS and genomic prediction results reported in our study.

Description
<p>This article is published as Corredor, Flor-Anita, Leticia P. Sanglard, Richard J. Leach, Jason W. Ross, Aileen F. Keating, and Nick VL Serão. "Genetic and genomic characterization of vulva size traits in Yorkshire and Landrace gilts." <em>BMC Genetics</em> 21 (2020): 28. doi: <a href="https://doi.org/10.1186/s12863-020-0834-9">10.1186/s12863-020-0834-9</a>.</p>
Keywords
Genetic parameters, Vulva size, Reproduction, Gilts, GWAS, Genomic prediction
Citation
Collections