Genetic and genomic characterization of vulva size traits in Yorkshire and Landrace gilts

dc.contributor.author Corredor, Flor-Anita
dc.contributor.author Sanglard, Leticia
dc.contributor.author Leach, Richard
dc.contributor.author Keating, Aileen
dc.contributor.author Ross, Jason
dc.contributor.author Keating, Aileen
dc.contributor.author Serão, Nick
dc.contributor.department Animal Science
dc.contributor.department Iowa Pork Industry Center
dc.date 2020-03-18T17:23:32.000
dc.date.accessioned 2020-06-29T23:41:35Z
dc.date.available 2020-06-29T23:41:35Z
dc.date.copyright Wed Jan 01 00:00:00 UTC 2020
dc.date.issued 2020-03-12
dc.description.abstract <p>Background: Reproductive performance is critical for efficient swine production. Recent results indicated that vulva size (VS) may be predictive of reproductive performance in sows. Study objectives were to estimate genetic parameters, identify genomic regions associated, and estimate genomic prediction accuracies (GPA) for VS traits.</p> <p>Results: Heritability estimates of VS traits, vulva area (VA), height (VH), and width (VW) measurements, were moderately to highly heritable in Yorkshire, with 0.46 ± 0.10, 0.55 ± 0.10, 0.31 ± 0.09, respectively, whereas these estimates were low to moderate in Landrace, with 0.16 ± 0.09, 0.24 ± 0.11, and 0.08 ± 0.06, respectively. Genetic correlations within VS traits were very high for both breeds, with the lowest of 0.67 ± 0.29 for VH and VW for Landrace. Genome-wide association studies (GWAS) for Landrace, reveled genomic region associated with VS traits on Sus scrofa chromosome (SSC) 2 (154–157Mb), 7 (107–110 Mb), 8 (4–6Mb), and 10 (8–19 Mb). For Yorkshire, genomic regions on SSC 1 (87–91 and 282–287Mb) and 5 (67Mb) were identified. All regions explained at least 3.4% of the genetic variance. Accuracies of genomic prediction were moderate in Landrace, ranging from 0.30 (VH) to 0.61 (VA), and lower for Yorkshire, with 0.07 (VW) to 0.11 (VH). Between-breed and multi-breed genomic prediction accuracies were low.</p> <p>Conclusions: Our findings suggest that VS traits are heritable in Landrace and Yorkshire gilts. Genomic analyses show that major QTL control these traits, and they differ between breed. Genomic information can be used to increase genetic gains for these traits in gilts. Additional research must be done to validate the GWAS and genomic prediction results reported in our study.</p>
dc.description.comments <p>This article is published as Corredor, Flor-Anita, Leticia P. Sanglard, Richard J. Leach, Jason W. Ross, Aileen F. Keating, and Nick VL Serão. "Genetic and genomic characterization of vulva size traits in Yorkshire and Landrace gilts." <em>BMC Genetics</em> 21 (2020): 28. doi: <a href="https://doi.org/10.1186/s12863-020-0834-9">10.1186/s12863-020-0834-9</a>.</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/ans_pubs/533/
dc.identifier.articleid 1534
dc.identifier.contextkey 16897716
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath ans_pubs/533
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/9971
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/ans_pubs/533/2020_Keating_GeneticGenomic.pdf|||Sat Jan 15 00:51:21 UTC 2022
dc.source.uri 10.1186/s12863-020-0834-9
dc.subject.disciplines Agriculture
dc.subject.disciplines Animal Sciences
dc.subject.disciplines Genetics and Genomics
dc.subject.keywords Genetic parameters
dc.subject.keywords Vulva size
dc.subject.keywords Reproduction
dc.subject.keywords Gilts
dc.subject.keywords GWAS
dc.subject.keywords Genomic prediction
dc.title Genetic and genomic characterization of vulva size traits in Yorkshire and Landrace gilts
dc.type article
dc.type.genre article
dspace.entity.type Publication
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relation.isOrgUnitOfPublication 85ecce08-311a-441b-9c4d-ee2a3569506f
relation.isOrgUnitOfPublication df954896-4d5d-4488-834b-cb21151374e8
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