Poultry Immunogenetics: Which Way Do We Go?

dc.contributor.author Lamont, Susan
dc.contributor.author Lamont, Susan
dc.contributor.department Animal Science
dc.date 2021-04-14T20:16:18.000
dc.date.accessioned 2021-04-29T23:53:22Z
dc.date.available 2021-04-29T23:53:22Z
dc.date.copyright Sat Jan 01 00:00:00 UTC 1994
dc.date.issued 1994-07-01
dc.description.abstract <p>A major goal in poultry immunogenetics is the enhancement of innate immunoresponsiveness and resistance to disease. This may be pursued by studying either single genes or polygenic traits. The MHC is perhaps the best-characterized family of host genes that modulates response to a variety of antigens and pathogenic challenges. The association of different MHC alleles with disease resistance has been known for decades. But only recently has analysis at the DNA level opened new avenues of understanding and new opportunities for application of genetic variation in the MHC with immunoresponsiveness. An alternate approach to molecular analysis is selection for a desired phenotype controlled by polygenes. Several studies have illustrated the successful alteration of immunoresponsiveness by genetic selection for antibody production. Recently, a selection program based upon multiple traits of immune response was conducted. Results of this project demonstrated that selection on multiple immune-response traits altered immunophysiology, MHC allelic frequencies, and disease resistance. Several areas for future pursuits in poultry immunogenetics research are proposed.</p>
dc.description.comments <p>This article is published as Lamont, S. J. "Poultry Immunogenetics: Which Way Do We Go?" <em>Poultry Science</em> 73, no. 7 (1994): 1044-1048. DOI: <a href="https://doi.org/10.3382/ps.0731044" target="_blank">10.3382/ps.0731044</a>. Posted with permission.</p>
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dc.identifier archive/lib.dr.iastate.edu/ans_pubs/837/
dc.identifier.articleid 1836
dc.identifier.contextkey 22482478
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath ans_pubs/837
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/104591
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/ans_pubs/837/1994_LamontSusan_PoultryImmunogenetics.pdf|||Sat Jan 15 02:10:23 UTC 2022
dc.source.uri 10.3382/ps.0731044
dc.subject.disciplines Agriculture
dc.subject.disciplines Animal Sciences
dc.subject.disciplines Genetics
dc.subject.disciplines Poultry or Avian Science
dc.subject.keywords major histocompatibility complex
dc.subject.keywords immune response
dc.subject.keywords genetics
dc.subject.keywords selection
dc.subject.keywords disease
dc.title Poultry Immunogenetics: Which Way Do We Go?
dc.type article
dc.type.genre article
dspace.entity.type Publication
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relation.isOrgUnitOfPublication 85ecce08-311a-441b-9c4d-ee2a3569506f
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