Reduction of antibiotic use after implementation of Ingelvac® PRRS MLV piglet vaccination in a Belgian wean to finish farm

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Van Looveren, F.
De Jonghe, E.
Maass, P.
De Backer, P.
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International Conference on the Epidemiology and Control of Biological, Chemical and Physical Hazards in Pigs and Pork
Iowa State University Conferences and Symposia

The SafePork conference series began in 1996 to bring together international researchers, industry, and government agencies to discuss current Salmonella research and identify research needs pertaining to both pig and pork production. In subsequent years topics of research presented at these conferences expanded to include other chemical and biological hazards to pig and pork production.


Porcine Reproductive and Respiratory Syndrome (PRRS) infections play an important role in Porcine Respiratory Disease Complex (PRDC). The aim of this study was to evaluate the effect of implementing a PRRS MLV vaccine, as an aid to control PRDC, on the antibiotic use in piglets and fatteners.

The study was performed in a wean-to-finish farm. Piglets were vaccinated upon arrival. In 2012, piglets were only vaccinated against Mycoplasma hyopneumoniae (M. hyo) with Ingelvac MycoFLEX®. As from 2013, Ingelvac® PRRS MLV was applied at the same time as the Mycoplasma hyopneumoniae (M. hyo) vaccine, at the other side of the neck. The reason for implementing the PRRS MLV vaccine were PRDC problems occurring at the end of 2012, including cough and poor performance in the nursery and fattening period. Presence of the PRRS virus was confirmed by serology.

A retrospective analysis of the antibiotic use and costs was performed over a 1-year-period before implementation of PRRS vaccination, an intermediate period of 6 months (PRRS vaccinated and non-vaccinated pigs were present) and a period of 1 year in which only PRRS vaccinated pigs were present on the farm.

In the period before PRRS vaccination, 18.56 g active substance/pig place/year was used, equal to an average of 29.3 daily doses/animal year. In the transition period, the antibiotic consumption equalled 20.82 g active substance/pig place/year or 33.6 daily doses/animal year. In the period after the PRRS vaccine implementation, 12.04 g active substance/pig place/year or 13.5 daily doses/animal year was used. The antibiotic costs equalled respectively 3.40€, 4.35€, 1.85€ per pig place per year in the 3 subsequent periods.

Antibiotic use expressed in daily doses/animal year was reduced by 53.9% and antibiotic costs by 45.6% after implementation of PRRS vaccination compared to the period before PRRS vaccination. Furthermore, the use of antibiotics considered as highly important for human medicine (red class) was reduced with 97.4%. Besides the reduction in antibiotic use, an improvement of the technical performance of the pigs was also observed.

Thu Jan 01 00:00:00 UTC 2015