Data-Driven Theory Refinement Algorithms for Bioinformatics

Date
1999
Authors
Yang, Jihoon
Dobbs, Drena
Parekh, Rajesh
Honavar, Vasant
Dobbs, Drena
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Zoology and Genetics
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Computer Science
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Zoology and GeneticsComputer Science
Abstract

Bioinformatics and related applications call for efficient algorithms for knowledge intensive learning and data driven knowledge refinement. Knowledge based artificial neural networks offer an attractive approach to extending or modifying incomplete knowledge bases or domain theories. We present results of experiments with several such algorithms for data driven knowledge discovery and theory refinement in some simple bioinformatics applications. Results of experiments on the ribosome binding site and promoter site identification problems indicate that the performance of KBDistAl and Tiling Pyramid algorithms compares quite favorably with those of substantially more computationally demanding techniques.

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This is a proceeding from International Joint Conference on Neural Networks (1999): 4064, doi: 10.1109/IJCNN.1999.830811. Posted with permission.

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