A polyanhydride-based implantable single dose vaccine platform for long-term immunity

Date
2018-02-08
Authors
Jackman, John
Schaut, Robert
Brewer, Matt
Brewer, Matt
Mendoza, Kriscelle
Jackman, John
Narasimhan, Balaji
Jones, Douglas
Narasimhan, Balaji
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Veterinary PathologyChemical and Biological EngineeringIndustrial and Manufacturing Systems EngineeringNanovaccine Institute
Abstract

Traditionally, immune priming followed by an antigen-boost is utilized for vaccine-induced protective immunity and maintaining long-term immunity often requires repeated exposure to antigen. Here, a novel single dose vaccination platform designed with gonadotropin releasing hormone multiple antigenic peptide as a model antigen is shown.

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This article is published as Schaut, Robert G., Matthew T. Brewer, Kriscelle Mendoza, John Jackman, Balaji Narasimhan, and Douglas E. Jones. "A polyanhydride-based implantable single dose vaccine platform for long-term immunity." Vaccine 36, no. 7 (2018): 1024-1025. DOI: 10.1016/j.vaccine.2017.11.067.

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