Long Polar Fimbriae Contribute to Colonization by Escherichia coli O157:H7 In Vivo

Date
2004-10-01
Authors
Jordan, Dianna
Cornick, Nancy
Cornick, Nancy
Torres, Alfredo
Dean-Nystrom, Evelyn
Kaper, James
Moon, Harley
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Veterinary PathologyVeterinary Microbiology and Preventive Medicine
Abstract

The contribution of long polar fimbriae to intestinal colonization by Escherichia coli O157:H7 was evaluated in sheep, conventional pigs, and gnotobiotic piglets.E. coli O157:H7 strains with lpfA1 and lpfA2 mutated were recovered in significantly lower numbers and caused fewer attachment and effacement lesions than the parent strain.

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This article is from Infection and Immunity 72 (2004): 6168, doi:10.1128/IAI.72.10.6168-6171.2004.

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