Trace mineral supplementation during times of stress and critical production periods may prove beneficial to overall animal health and performance. A decrease in trace mineral status may negatively impact reproduction, immunity, and general performance of the animal. Little research is available inquiring into breed differences on trace mineral status and clearance. This study concluded that Multimin®90 appeared to be an effective way to improve the trace mineral status, specifically of liver copper (Cu) and selenium (Se), of Angus and Simmental calves when compared to controls receiving sterilized saline.