Porcine astrovirus type 3 is an emerging cause of atypical neurologic disease: Diagnostic cases and infection dynamics on affected flows

Date
2019-01-01
Authors
Rawal, Gaurav
Matias Ferreyra, Franco
Linhares, Daniel
Mueller, Adam
Allison, Grant
Hedberg, William
Macedo, Nubia
Bradner, Laura
Harmon, Karen
Linhares, Daniel
Arruda, Bailey
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Veterinary Diagnostic and Production Animal Medicine
Abstract

Astroviruses (AstVs) are viral agents in the Family Astroviridae that are able to infect and cause disease in a wide variety of host species. Despite the broad host range and ability to cause disease, there are significant gaps in knowledge concerning the epidemiology, ecology, and pathophysiology of a majority of AstVs. Porcine astroviruses (PoAstVs) are distributed worldwide. Five PoAstV lineages (PoAstV1–PoAstV5) have been identified perhaps reflecting diverse origins, interspecies transmission, and recombination events, some presumably with human strains. In the past decade, different members of the genus Mamastrovirus have been associated with neurologic disease in humans, bovine, mink and most recently, porcine astrovirus 3 (PoAstV3) in swine.

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Rawal, Gaurav, F. F. Matias, Adam Mueller, Grant Allison, William Hedberg, Nubia Macedo, Laura Bradner, Karen Harmon, Daniel Linhares, and Bailey Arruda. "Porcine astrovirus type 3 is an emerging cause of atypical neurologic disease: Diagnostic cases and infection dynamics on affected flows." In Proceedings of the 50th Annual Meeting of the American Association of Swine Veterinarians. Orlando, FL, USA. (2019): 9-12. Posted with permission.

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