Peritoneal fibrosarcomatous mesothelioma in a cat

dc.contributor.author Heerkens, Tammy
dc.contributor.author Smith, Jodi
dc.contributor.author Fox, Leslie
dc.contributor.author Smith, Jodi
dc.contributor.author Hostetter, Jesse
dc.contributor.department Veterinary Pathology
dc.contributor.department Veterinary Clinical Sciences
dc.date 2018-02-18T22:44:18.000
dc.date.accessioned 2020-07-07T05:16:12Z
dc.date.available 2020-07-07T05:16:12Z
dc.date.issued 2011-05-01
dc.description.abstract <p>Primary tumors of serosal surfaces are uncommon in veterinary medicine. Mesothelial neoplasms can be benign or malignant, and are classified as predominantly epitheloid, mixed (biphasic), or fibrous (spindle cell, fibrosarcomatous), with fibrous mesotheliomas reported least in domestic species. A 9-year-old Domestic Shorthair cat presented on emergency with a brief history of weakness and lethargy. On presentation, the cat was semicomatose, hypothermic, and hypotensive with a markedly distended abdomen. Approximately 1 liter of serosanguineous fluid was removed via abdominocentesis. Diagnostic imaging and cytologic evaluation of fine-needle aspirates were suggestive of neoplasia, and the cat was subsequently euthanized. At necropsy, the omentum was contracted cranially into an irregular lobular mass that surrounded the stomach and proximal intestinal tract, and focally infiltrated the spleen. Both visceral and parietal peritoneal surfaces were thickened and contained off-white friable material and occasionally firm fibrous plaques. Microscopically, serosal surfaces were expanded by neoplastic spindle cells, which were often accompanied by moderate to abundant fibrous stroma. Neoplastic cells had varying degrees of immunoreactivity for cytokeratin, vimentin, desmin, and smooth muscle actin, which was consistent with the diagnosis of mesothelioma.</p>
dc.description.comments <p>This article is published as Heerkens, Tammy MJ, Jodi D. Smith, Leslie Fox, and Jesse M. Hostetter. "Peritoneal fibrosarcomatous mesothelioma in a cat." Journal of veterinary diagnostic investigation 23, no. 3 (2011): 593-597. doi:<a href="https://doi.org/10.1177/1040638711403405"> 10.1177/1040638711403405</a>. Posted with permission.</p>
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dc.identifier archive/lib.dr.iastate.edu/vpath_pubs/87/
dc.identifier.articleid 1090
dc.identifier.contextkey 10727950
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath vpath_pubs/87
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/92516
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/vpath_pubs/87/2011_Smith_PeritonealFibrosarcomatous.pdf|||Sat Jan 15 02:15:39 UTC 2022
dc.source.uri 10.1177/1040638711403405
dc.subject.disciplines Small or Companion Animal Medicine
dc.subject.disciplines Veterinary Medicine
dc.subject.disciplines Veterinary Microbiology and Immunobiology
dc.subject.disciplines Veterinary Pathology and Pathobiology
dc.subject.keywords Abdominal cavity
dc.subject.keywords cancer
dc.subject.keywords cats
dc.subject.keywords feline
dc.subject.keywords fibrosarcomatous
dc.subject.keywords mesothelioma
dc.title Peritoneal fibrosarcomatous mesothelioma in a cat
dc.type article
dc.type.genre article
dspace.entity.type Publication
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