The Impacts of SARS-CoV-2 on Chronic Kidney Disease
Date
2023-05
Authors
Tappa, Victoria
Major Professor
Kimber, Michael
Blitvich, Bradley
Advisor
Committee Member
Bracha, Vlastislav
Lyons, Michael
Greenlee, Heather
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Abstract
This literature review offers insight into how SARS-CoV-2 has impacted Chronic Kidney Disease (CKD). Since the start of the COVID-19 pandemic, the incidence and prevalence of CKD cases and stage progression has been evident and alarming. Both diseases have a higher prevalence in older populations, those of racial and ethnic minorities, people who have difficulty accessing healthcare, and individuals with risk factors such as type II diabetes mellitus, hypertension, obesity, and cardiovascular disease. The intricate relationship of the Renin-Angiotensin-Aldosterone System (RAAS) and modifications to the ACE2 receptor help explain how SARS-CoV-2 impacts CKD. The role of social determinants of health, co-morbidities, and their influences on both diseases in this review cannot be overstated. This review suggests SARS-CoV-2 as a root cause for CKD emergence, stage progression, and decreased CKD care delivery.
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creative component
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Copyright
2023