Astroviruses (AstVs) are non-enveloped, 28-30 nm, positive-sense, single-stranded RNA viruses with a genome that varies from 6.4 to 7.3 kb. Astroviruses have been demonstrated to infect a wide variety of animals, both domestic and wild, including avian and mammalian species in terrestrial and aquatic environments.1 Despite the broad host range and ability to cause disease, there are significant gaps in knowledge concerning the epidemiology, ecology, and pathophysiology of most AstVs.