Veterinary Considerations for the Theoretical Resurrection of Extinct Species

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Smith, Joe
Feye, K. M.
Smith, Joseph
Sebbag, Lionel
Sebbag, Lionel
Hohman, A. E.
Acharya, Sreemoyee
Schneider, Benjamin
Tucker, J. T.
Cherep, Lucia
Nordeng, B. R.
Richardson, A. L.
Gage, Meghan
Luo, Diou
Shrestha, Denusha
Izbicki, Patricia
Malovic, Emir
Jefferson, M. A.
Manne, Sireesha
Jaisil, Pongrat
Kondru, Naveen
Massey, Nyzil
Klinedinst, Brandon
Carlson, Steve
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Biomedical SciencesVeterinary Clinical SciencesNeuroscienceKinesiologyPsychologyVeterinary Diagnostic and Production Animal MedicineNeuroscience

The de-extinction of the dinosaur is a dubious possibility but its consideration brings forth some issues that are at least worthy of scientific discussion. In this review, we discuss two distinct issues that have implications for a de-extinct species such as a dinosaur: the ability, or lack thereof, to safely sedate a rare and potentially fractious animal capable of harming the veterinary staff tasked with its care; and, disease risks associated with a species that has been extinct for millions of years. To identify potential sedatives, comparative pharmacology will be needed to uncover the links between receptor pharmacology and the desired clinical outcomes of activating established alpha-2 adrenergic, opioid, and benzodiazepine receptors. Specific to disease control, it will be necessary to understand the unique susceptibility of the new species to current diseases as well as predicting their reservoir capacity for potential human and veterinary pandemic diseases. While the topics presented herein are not exhaustive, this review highlights some of the foremost research that should be conducted in order to serve the unique veterinary needs of a de-extinct species using the dinosaur as a paradigm. Addressing these issues should be considered if an intact dinosaur genome becomes available, regardless of the feasibility of dinosaur resurrection.


This article is published as Feye KM, Smith JS, Sebbag L, Hohman AE, Acharya S, Schneider BK, Tucker JT, Cherep LA, Nordeng BR, Richardson AL, Gage MC, Luo D, Shrestha D, Izbicki P, Malovic E, Jefferson MA, Manne S, Jaisil P, Kondru NC, Massey N, Klinedinst BS, and Carlson SA. "Veterinary Considerations for the Theoretical Resurrection of Extinct Species." Journal of Veterinary Science & Animal Husbandry 6, no. 3 (2018): 306. Posted with permission.