Self-Immolative Phthalate Esters Sensitive to Hydrogen Peroxide and Light

dc.contributor.author Mahoney, Kaitlyn
dc.contributor.author Goswami, Pratik
dc.contributor.author Ayed, Aleem
dc.contributor.author Kolker, Patrick
dc.contributor.author Smith, Emily
dc.contributor.author Shannan, Brian
dc.contributor.author Winter, Arthur
dc.contributor.department Chemistry
dc.date 2018-02-17T09:44:51.000
dc.date.accessioned 2020-06-30T01:23:39Z
dc.date.available 2020-06-30T01:23:39Z
dc.date.copyright Wed Jan 01 00:00:00 UTC 2014
dc.date.issued 2014-11-10
dc.description.abstract <p>Self-immolative aryl phthalate esters were conjugated with cleavable masking groups sensitive to light and hydrogen peroxide. The phthalate linker releases the fluorescent dye 7-hydroxycoumarin upon exposure to light or H2O2, respectively, leading to an increase in fluorescence. The light-sensitive aryl phthalate ester is demonstrated as a pro- fluorophore in cultured S2 cells</p>
dc.description.comments <p>Reprinted (adapted) with permission from <em>The Journal of Organic Chemistry, </em>79(23); 11740-11743. Doi: <a href="http://dx.doi.org/10.1021/jo501900h" target="_blank">10.1021/jo501900h</a>. Copyright 2014 American Chemical Society.</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/chem_pubs/887/
dc.identifier.articleid 1879
dc.identifier.contextkey 7969027
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath chem_pubs/887
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/15386
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/chem_pubs/887/0-2014_SmithEA_ACS_License_SelfImmolativePhthalate.pdf|||Sat Jan 15 02:18:02 UTC 2022
dc.source.bitstream archive/lib.dr.iastate.edu/chem_pubs/887/2014_SmithEA_SelfImmolativePhthalate.pdf|||Sat Jan 15 02:18:03 UTC 2022
dc.source.uri 10.1021/jo501900h
dc.subject.disciplines Chemistry
dc.subject.disciplines Inorganic Chemistry
dc.subject.disciplines Materials Chemistry
dc.subject.disciplines Organic Chemistry
dc.subject.disciplines Other Chemistry
dc.subject.disciplines Polymer Chemistry
dc.title Self-Immolative Phthalate Esters Sensitive to Hydrogen Peroxide and Light
dc.type article
dc.type.genre article
dspace.entity.type Publication
relation.isAuthorOfPublication 1593ba6f-2eb3-4290-ab73-86b7601506fa
relation.isAuthorOfPublication a2121da6-c591-494f-b9a9-595265e46ff9
relation.isOrgUnitOfPublication 42864f6e-7a3d-4be3-8b5a-0ae3c3830a11
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