Measured and calculated variables of global oxygenation in healthy neonatal foals

dc.contributor.author Wong, David
dc.contributor.author Hepworth-Warren, Kate
dc.contributor.author Sponseller, Beatrice
dc.contributor.author Howard, Joan
dc.contributor.author Wang, Chong
dc.contributor.department Veterinary Clinical Sciences
dc.contributor.department Veterinary Diagnostic and Production Animal Medicine
dc.date 2018-06-19T23:07:27.000
dc.date.accessioned 2020-07-07T05:12:41Z
dc.date.available 2020-07-07T05:12:41Z
dc.date.copyright Sun Jan 01 00:00:00 UTC 2017
dc.date.issued 2017-02-01
dc.description.abstract <p>OBJECTIVE To assess multiple central venous and arterial blood variables that alone o r in conjunction with one another reflect global oxygenation status in healthy neonatal foals.</p> <p>ANIMALS 11 healthy neonatal foals.</p> <p>PROCEDURES Central venous and arterial blood samples were collected from healthy neonatal foals at 12, 24, 36, 48, 72, and 96 hours after birth. Variables measured from central venous and arterial blood samples included oxygen saturation of hemoglobin, partial pressure of oxygen, lactate concentration, partial pressure of carbon dioxide, and pH. Calculated variables included venous-to-arterial carbon dioxide gap, estimated oxygen ext raction ratio, ratio of partial pressure of oxygen in arterial blood to the fraction of inspired oxygen, bicarbonate concentration, base excess, and blood oxygen content.</p> <p>RESULTS Significant differences between arterial and central venous blood obtained from neonatal foals were detected for several variables, particularly partial pressure of oxygen, oxygen saturation of hemoglobin, and oxygen content. In addition, the partial pressure of carbon dioxide in central venous blood samples was significantly higher than the value for cor responding arterial blood samples. Several temporal differences were detected for other variables.</p> <p>CONCLUSIONS AND CLINICAL RELEVANCE Results of this study provided info rmation about several variables that reflect global oxygenation in healthy neonatal foals. Values for these variables in healthy foals can allow for comparison with values for critically ill foals in future studies. Comparison of these variables between healthy and ill foals may aid in treatment decisions and prognosis of clinical outcome for crit ically ill foals.</p>
dc.description.comments <p>This article is published as Wong, David M., Kate L. Hepworth-Warren, Beatrice T. Sponseller, Joan M. Howard, and Chong Wang. "Measured and calculated variables of global oxygenation in healthy neonatal foals." <em>American journal of veterinary research</em> 78, no. 2 (2017): 230-238. doi: <a href="https://doi.org/10.2460/ajvr.78.2.230">10.2460/ajvr.78.2.230</a>. Posted with permission.</p>
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dc.identifier archive/lib.dr.iastate.edu/vdpam_pubs/116/
dc.identifier.articleid 1119
dc.identifier.contextkey 12341482
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath vdpam_pubs/116
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/91957
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/vdpam_pubs/116/0-Wang_AVMA_Permission.pdf|||Fri Jan 14 18:54:09 UTC 2022
dc.source.bitstream archive/lib.dr.iastate.edu/vdpam_pubs/116/2016_Wang_MeasuredCalculated.pdf|||Fri Jan 14 18:54:11 UTC 2022
dc.source.uri 10.2460/ajvr.78.2.230
dc.subject.disciplines Large or Food Animal and Equine Medicine
dc.subject.disciplines Veterinary Physiology
dc.subject.disciplines Veterinary Preventive Medicine, Epidemiology, and Public Health
dc.title Measured and calculated variables of global oxygenation in healthy neonatal foals
dc.type article
dc.type.genre article
dspace.entity.type Publication
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