Induction of resistant mutants of Salmonella typhimurium under enrofloxacin and natural alternatives for control in pigs
Is Version Of
The SafePork conference series began in 1996 to bring together international researchers, industry, and government agencies to discuss current Salmonella research and identify research needs pertaining to both pig and pork production. In subsequent years topics of research presented at these conferences expanded to include other chemical and biological hazards to pig and pork production.
The increase in bacterial resistance to Enrofloxacin (ENR) in recent years has been associated with the selective growth of single-step mutant strains resistant to the frequent dose in use, based on the Minimum Inhibitory Concentration (MIC). Because of that, it is supported the need to establish optimal dosage intervals taking into account the minimum concentration of antibiotic capable of inhibiting the growth of pre-existing or first pass mutant strains: Mutant Prevention Concentration (MPC). Therefore, it is of importance to maintain the antimicrobial and molecular monitoring of quinolones and to search for new alternatives, such as the use of essential oils for the control of salmonellosis.