SARS-CoV-2: Current Therapeutics Human and Veterinary Medicine

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Date
2020-01-01
Authors
Garcia, Andrea
Major Professor
Jonathan Mochel
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Biomedical Sciences

The Department of Biomedical Sciences aims to provide knowledge of anatomy and physiology in order to understand the mechanisms and treatment of animal diseases. Additionally, it seeks to teach the understanding of drug-action for rational drug-therapy, as well as toxicology, pharmacodynamics, and clinical drug administration.

History
The Department of Biomedical Sciences was formed in 1999 as a merger of the Department of Veterinary Anatomy and the Department of Veterinary Physiology and Pharmacology.

Dates of Existence
1999–present

Related Units

  • College of Veterinary Medicine (parent college)
  • Department of Veterinary Anatomy (predecessor, 1997)
  • Department of Veterinary Physiology and Pharmacology (predecessor, 1997)

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Abstract

The Severe Acute Respiratory Syndrome Coronavirus 2, SARS-CoV-2, was first reported in Wuhan City, China, in December 2019. Health and environmental risk factors are crucial in this current pandemic, yet it is essential to note that even though individuals of all ages are susceptive to this virus, there are risk factors associated with developing the severe disease. It is also eminent to establish the human-animal interaction by tackling important past pathogenic viruses such as SARS-CoV and MERS-CoV and its zoonotic links. In need of a clinically established management for this outbreak, approved drugs' therapeutic interventions could help treat this disease, targeting its replication. The need to resolve the current pandemic of COVID-19 epitomizes the need for a different approach, drug repurposing. Characterization of artificial intelligence created by predicted models and structures could alleviate COVID-19; it has been used not only in the development of drugs but also in tackling screening, treatment, and contact tracing. This review presents pathogenesis, transmission, and the analysis of drug repositioning in both human and veterinary medicine of SARS-CoV-2 to delve into practical approaches to manage this disease.

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Wed Jan 01 00:00:00 UTC 2020