The minimum (symmetric) rank of a simple graph G over a field F is the smallest possible rank among all symmetric matrices over F whose ijth entry (for i≠j) is nonzero whenever {i,j} is an edge in G and is zero otherwise. The problem of determining minimum (symmetric) rank has been studied extensively. We define the minimum skew rank of a simple graph G to be the smallest possible rank among all skew-symmetric matrices over F whose ijth entry (for i≠j) is nonzero whenever {i,j} is an edge in G and is zero otherwise. We apply techniques from the minimum (symmetric) rank problem and from skew-symmetric matrices to obtain results about the minimum skew rank problem.