Effects of d-α-Tocopherol and Dietary Energy on Growth and Health of Pre-Ruminant Dairy Calves

Date
2014-01-01
Authors
Krueger, Lucas
Beitz, Donald
Onda, Ken
Osman, Mohammed
O'Neil, Mathew
Lei, Samantha
Stuart, Robert
Tyler, Howard
Nonnecke, Brian
Major Professor
Advisor
Committee Member
Journal Title
Journal ISSN
Volume Title
Publisher
Altmetrics
Authors
Research Projects
Organizational Units
Journal Issue
Series
Department
Abstract

Newborn Holstein bull calves were fed milk to support low or moderate growth and were supplemented with a complement of vitamins A, D, and E. The objective of the study was to determine the effects of dietary energy and vitamin supplementation on inflammation at the whole-body level. Calves were assigned randomly to one of four treatment groups (low growth, not vitamin supplemented; low growth, vitamin supplemented; moderate growth, not vitamin supplemented; moderate growth, vitamin supplemented) for five weeks. Vitamin supplementation tended to improve average daily gain in moderate-growth calves and significantly increased concentrations of retinol, 25-(OH)-vitamin D, and α-tocopherol in plasma in supplemented groups. Moderate growth calves exhibited lower concentrations of α-tocopherol in plasma and higher concentrations of serum haptoglobin, which is a protein associated with chronic inflammation. All calves exhibited elevated concentrations of the more acute indicator of inflammation, serum amyloid A, during weeks 1-3. These results indicate potential roles for vitamins A, D, and E in moderation of pro-inflammatory responses early in life.

Comments
Description
Keywords
Citation
Source
Collections