Stage-Specific Suppression of Basal Defense Discriminates Barley Plants Containing Fast- and Delayed-Acting Mla Powdery Mildew Resistance Alleles

dc.contributor.author Caldo, Rico
dc.contributor.author Nettleton, Dan
dc.contributor.author Nettleton, Dan
dc.contributor.author Peng, Jiqing
dc.contributor.author Wise, Roger
dc.contributor.department Plant Pathology and Microbiology
dc.contributor.department Statistics
dc.date 2019-08-25T02:45:36.000
dc.date.accessioned 2020-07-02T06:57:13Z
dc.date.available 2020-07-02T06:57:13Z
dc.date.issued 2006-09-01
dc.description.abstract <p>Nonspecific recognition of pathogen-derived general elicitors triggers the first line of plant basal defense, which in turn, preconditions the host towards resistance or susceptibility. To elucidate how basal defense responses influence the onset of <em>Mla</em> (mildew resistance locus <em>a</em>)-specified resistance, we performed a meta-analysis of GeneChip mRNA expression for 155 basal defense-related genes of barley (<em>Hordeum vulgare</em>) challenged with <em>Blumeria graminis</em> f. sp. <em>hordei</em>, the causal agent of powdery mildew disease. In plants containing the fast-acting <em>Mla1</em>, <em>Mla6</em>, or <em>Mla13</em> alleles, transcripts hyper-accumulated from 0 to 16 h after inoculation (hai) in both compatible and incompatible interactions. Suppression of basal defense-related transcripts was observed after 16 hai only in compatible interactions, whereas these transcripts were sustained or increased in incompatible interactions. By contrast, in plants containing wild-type and mutants of the delayed-acting <em>Mla12</em> allele, an early hyper-induction of transcripts from 0 to 8 hai was observed, but the expression of many of these genes is markedly suppressed from 8 to 16 hai. These results suggest that the inhibition of basal defense facilitates the development of haustoria by the pathogen, consequently delaying the onset of host resistance responses. Thus, we hypothesize that the regulation of basal defense influences host-cell accessibility to the fungal pathogen and drives allelic diversification of gene-specific resistance phenotypes.</p>
dc.description.comments <p>This article is published as Caldo, Rico A., Dan Nettleton, Jiqing Peng, and Roger P. Wise. "Stage-specific suppression of basal defense discriminates barley plants containing fast-and delayed-acting Mla powdery mildew resistance alleles." <em>Molecular Plant-Microbe Interactions</em> 19, no. 9 (2006): 939-947. doi: <a href="https://doi.org/10.1094/MPMI-19-0939">10.1094/MPMI-19-0939</a>.</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/stat_las_pubs/211/
dc.identifier.articleid 1217
dc.identifier.contextkey 14861479
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath stat_las_pubs/211
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/90523
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/stat_las_pubs/211/2006_Nettleton_StageSpecific.pdf|||Fri Jan 14 22:34:51 UTC 2022
dc.source.uri 10.1094/MPMI-19-0939
dc.subject.disciplines Agronomy and Crop Sciences
dc.subject.disciplines Microarrays
dc.subject.disciplines Plant Breeding and Genetics
dc.subject.disciplines Plant Pathology
dc.subject.disciplines Statistical Methodology
dc.subject.keywords innate immunity
dc.subject.keywords pathogen-associated molecular patterns
dc.subject.keywords timing of resistance response
dc.title Stage-Specific Suppression of Basal Defense Discriminates Barley Plants Containing Fast- and Delayed-Acting Mla Powdery Mildew Resistance Alleles
dc.type article
dc.type.genre article
dspace.entity.type Publication
relation.isAuthorOfPublication 7d86677d-f28f-4ab1-8cf7-70378992f75b
relation.isOrgUnitOfPublication a26b5928-54bb-4a0b-a973-95d649d1ad83
relation.isOrgUnitOfPublication 264904d9-9e66-4169-8e11-034e537ddbca
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