Weed management is in a continual state of change, however there are several issues that will likely be major considerations for several years and reflect concerns for the environment and the economics of weed management. These issues include guaranteed performance agreements and the advisability of respray programs, herbicide resistance in weeds, herbicide resistant crops, the interaction of pesticides as it affects crop phytotoxicity and new herbicide products and associated environmental risks. This paper will briefly review these issues and provide the perspective of the authors about the impact of these issues on weed management.