Interaction between host cells and Salmonella Typhimurium isolates from septicemic pigs Bergeron, Nadia Corriveau, J. Letellier, Ann Daigle, F. Lessard, L. Quessy, Sylvain 2018-08-13T18:30:05.000 2020-07-02T06:21:49Z 2020-07-02T06:21:49Z Thu Jan 01 00:00:00 UTC 2009 2009-01-01
dc.description.abstract <p>In this study, we characterized isolates (n=33) from septicemia outbreaks in swine herds as well as isolates (n=33) recovered from healthy animals at slaughter. At first, the rates of adhesion and invasion on intestinal epithelial cell lines were measured for all isolates. The isolates recovered from diseased animals have been shown to invade at a higher rate (P < 0.05) than isolates from healthy pigs. There was no significant difference for adhesion between 2 groups of isolates (P > 0.05). Some isolates were chosen for the remaining experiments according to invasion assay results. No difference between isolates from septicemic pigs and isolates from healthy pigs was detected for other phenotypic methods such as phagocytosis rates and survival in monocytes, apoptosis, adhesion to intestinal mucus and microbial surface properties. However, for the phagocytosis rates, a significant difference between the 2 groups of isolates was observed at 15 minutes (P < 0.05). These results suggest that early steps in the infection and spread within host phagocytes can be important in the outcome of the disease caused by these virulent isolates.</p>
dc.format.mimetype application/pdf
dc.identifier archive/
dc.identifier.articleid 1878
dc.identifier.contextkey 6206978
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath safepork/2009/allpapers/69
dc.language.iso en
dc.relation.ispartofseries International Conference on the Epidemiology and Control of Biological, Chemical and Physical Hazards in Pigs and Pork
dc.source.bitstream archive/|||Sat Jan 15 01:30:12 UTC 2022
dc.subject.disciplines Animal Diseases
dc.subject.disciplines Veterinary Infectious Diseases
dc.subject.disciplines Veterinary Microbiology and Immunobiology
dc.subject.disciplines Veterinary Preventive Medicine, Epidemiology, and Public Health
dc.title Interaction between host cells and Salmonella Typhimurium isolates from septicemic pigs
dc.type event
dc.type.genre article
dspace.entity.type Publication
relation.isSeriesOfPublication aab46b45-e596-479d-af7f-e072b1599cd7
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