Effects of nitroethane and 2-nitropropanol against Campylobacter jejuni
Jung, Yong Soo
Campylobacter jejuni is an important foodborne pathogen that colonizes the gut of swine. In this study, the effects of nitroethane and 2-nitropropanol (0, 10 and 20 mM) on growth of C. jejuni were tested during culture in Bolton broth adjusted to pH of 5.6, 7.0 or 8.2. Viable cell counts of samples taken at intervals during incubation revealed main effects (P<0.0001) of nitroethane or 2-nitropropanol on mean specific growth rates thus demonstrating that these were inhibitory to C. jejuni. By 48 h of incubation, C. jejuni concentrations had increased by 1.9 log10 CFU/ml or higher in cultures containing no added nitrocompound.