Parameterization, geometric modeling, and isogeometric analysis of tricuspid valves Johnson, Emily Laurence, Devin Hsu, Ming-Chen Xu, Fei Crisp, Caroline Mir, Arshid Burkhart, Harold Lee, Chung-Hao Hsu, Ming-Chen
dc.contributor.department Mechanical Engineering 2021-06-28T18:00:44.000 2021-08-14T19:12:09Z 2021-08-14T19:12:09Z Fri Jan 01 00:00:00 UTC 2021 2023-06-17 2021-10-01
dc.description.abstract <p>Approximately 1.6 million patients in the United States are affected by <a href="" title="Learn more about tricuspid valve from ScienceDirect's AI-generated Topic Pages">tricuspid valve</a> <a href="" title="Learn more about regurgitation from ScienceDirect's AI-generated Topic Pages">regurgitation</a>, which occurs when the tricuspid valve does not close properly to prevent backward blood flow into the right atrium. Despite its critical role in proper cardiac function, the tricuspid valve has received limited research attention compared to the mitral and <a href="" title="Learn more about aortic valves from ScienceDirect's AI-generated Topic Pages">aortic valves</a> on the left side of the heart. As a result, proper valvular function and the pathologies that may cause dysfunction remain poorly understood. To promote further investigations of the <a href="" title="Learn more about biomechanical behavior from ScienceDirect's AI-generated Topic Pages">biomechanical behavior</a> and response of the tricuspid valve, this work establishes a parameter-based approach that provides a template for tricuspid valve <a href="" title="Learn more about modeling and simulation from ScienceDirect's AI-generated Topic Pages">modeling and simulation</a>. The proposed tricuspid valve parameterization presents a comprehensive description of the leaflets and the complex chordae tendineae for capturing the typical three-leaflet structural deformation observed from medical data. This simulation framework develops a practical procedure for modeling tricuspid valves and offers a robust, flexible approach to analyze the performance and effectiveness of various valve configurations using isogeometric analysis. The proposed methods also establish a baseline to examine the tricuspid valve’s structural deformation, perform future investigations of native valve configurations under healthy and disease conditions, and optimize prosthetic valve designs.</p>
dc.description.comments <p>This is a manuscript of an article published as Johnson, Emily L., Devin W. Laurence, Fei Xu, Caroline E. Crisp, Arshid Mir, Harold M. Burkhart, Chung-Hao Lee, and Ming-Chen Hsu. "Parameterization, geometric modeling, and isogeometric analysis of tricuspid valves." <em>Computer Methods in Applied Mechanics and Engineering</em> 384 (2021): 113960. DOI: <a href="" target="_blank">10.1016/j.cma.2021.113960</a>. Posted with permission.</p>
dc.format.mimetype application/pdf
dc.identifier archive/
dc.identifier.articleid 1489
dc.identifier.contextkey 23566186
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath me_pubs/487
dc.language.iso en
dc.source.bitstream archive/|||Sat Jan 15 00:28:37 UTC 2022
dc.source.uri 10.1016/j.cma.2021.113960
dc.subject.disciplines Biomechanical Engineering
dc.subject.disciplines Biomedical Devices and Instrumentation
dc.subject.keywords Isogeometric analysis
dc.subject.keywords Tricuspid valves
dc.subject.keywords Atrioventricular valves
dc.subject.keywords Valvular heart disease
dc.subject.keywords Parametric modeling
dc.subject.keywords Template-based approach
dc.title Parameterization, geometric modeling, and isogeometric analysis of tricuspid valves
dc.type article
dc.type.genre article
dspace.entity.type Publication
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