Synthesis and Testing of Compounds That Inhibit Soybean Cyst Nematode Egg Hatch
Vander Louw, Steven
Soybean cyst nematode infestation continues to be a serious agricultural problem. As part of an interdisciplinary effort to identify a biorational solution to the problem, analogs of glycinoeclepin A, a natural hatching stimulus of the nematode, were prepared and tested. Several of the analogs were discovered to inhibit the hatching of soybean cyst nematode eggs. On the basis of the results of egg hatch tests, the minimum functionality for egg hatch inhibition appears to be a keto diacid.
Reprinted (adapted) with permission from Kraus, George A., Steven J. Vander Louw, Gregory L. Tylka, and David H. Soh. "Synthesis and testing of compounds that inhibit soybean cyst nematode egg hatch." Journal of agricultural and food chemistry 44, no. 6 (1996): 1548-1550. Copyright 1996 American Chemical Society.