Evaluation of a fluorapatite-spinel ceramic as a bone implant

dc.contributor.author Aksaci, Denginur
dc.contributor.department Materials Science and Engineering
dc.date 2018-08-16T08:39:55.000
dc.date.accessioned 2020-07-02T05:57:33Z
dc.date.available 2020-07-02T05:57:33Z
dc.date.copyright Thu Jan 01 00:00:00 UTC 1981
dc.date.issued 1981
dc.description.abstract <p>The objective of this study was to produce a ceramic that can be used as a hard tissue implant. After investigation of several mixtures of tricalcium phosphate, calcium fluoride, magnesium carbonate and alumina, a composite of fluorapatite and spinel was selected as the ceramic material. The ability to prepare sound samples and the minimum solubility in tissue fluids were the main reasons for the selection of a composite with one mole of fluorapatite to three moles of magnesium aluminate spinel;The ceramic was tested to determine the effect of porosity on strength so that the optimum combination of microstructure and mechanical properties could be obtained. The effect of the duration of stay in the physiological environment on the bending strength was determined after in vitro tests in Ringer's solution for porous and non-porous bars, and also after in vivo tests of non-porous subcutaneous implants;Porous bone bridges implanted in dogs were studied in terms of bone ingrowth, implant stabilization and tissue compatibility. Thin sections of the bone-ceramic interface were prepared and analyzed using optical microscopy with polarized transmitted light;The results of the tests in vivo and in vitro showed that the fluorapatite-spinel ceramic can be successfully used as a permanent hard tissue implant.</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/rtd/6961/
dc.identifier.articleid 7960
dc.identifier.contextkey 6298719
dc.identifier.doi https://doi.org/10.31274/rtd-180813-5709
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath rtd/6961
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/79786
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/rtd/6961/r_8209092.pdf|||Sat Jan 15 01:31:19 UTC 2022
dc.subject.disciplines Materials Science and Engineering
dc.subject.keywords Materials science and engineering
dc.subject.keywords Metallurgy
dc.title Evaluation of a fluorapatite-spinel ceramic as a bone implant
dc.type article
dc.type.genre dissertation
dspace.entity.type Publication
relation.isOrgUnitOfPublication bf9f7e3e-25bd-44d3-b49c-ed98372dee5e
thesis.degree.level dissertation
thesis.degree.name Doctor of Philosophy
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