The literature has been reviewed for all existing types of amino acid resolution as well as for many experiments in other fields which could have a direct or indirect bearing on the problem of resolving unsubstituted amino acids;Twelve miscellaneous new compounds have been characterized for developmental purposes on synthetic methods;Five new optically active amines and four of their bioxalates have been characterized;Ten new quaternary halides and two new substituted guanidine sulfates (all optically active) have been characterized;Three new resolutions of amino acids have been described, involving four new diastereomeric salts;Twenty other strong organic base-amino acid combinations also were investigated, as well as miscellaneous other methods, including the use of optically active solvents or adsorbents; none of them resulted in resolution.