Opsonin-dependent stimulation of bovine neutrophil oxidative metabolism by Brucella abortus

dc.contributor.author Canning, Peter
dc.contributor.author Deyoe, Billy
dc.contributor.author Roth, James
dc.contributor.author Roth, James
dc.contributor.department Veterinary Microbiology and Preventive Medicine
dc.date 2018-04-12T18:47:29.000
dc.date.accessioned 2020-07-07T05:14:53Z
dc.date.available 2020-07-07T05:14:53Z
dc.date.issued 1988-02-01
dc.description.abstract <p>Nonopsonized Brucella abortus and bacteria treated with fresh antiserum, heat-inactivated antiserum, or normal bovine serum were evaluated for their ability to stimulate production of superoxide anion and myeloperoxidasemediated iodination by neutrophils from cattle. Brucella abortus opsonized with fresh antiserum or beat-inactivated antiserum stimulated production of approximately 3 nmol of 0 2 -/106 neutrophils/30 min. Similarly treated bacteria also stimulated the binding of approximately 4.3 nmol of Nal/107 neutrophils/h to protein. Significant CP < 0.05) production of 0 2 - and iodination activity by neutrophils were not stimulated by nonopsonized bacteria or organisms treated with normal bovine serum. Seemingly, B abortus stimulated oxidative metabolism in bovine neutrophils; however, the stimulation was dependent on the presence of bacterial usociated opsonins.</p>
dc.description.comments <p>This article is published as Canning, P.C., B.K. Deyoe, and J.A. Roth. 1988. Opsonin-dependent stimulation of bovine neutrophil oxidative metabolism by <em>Brucella abortus. </em>Am J Vet Res, 49:160-163.</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/vmpm_pubs/190/
dc.identifier.articleid 1192
dc.identifier.contextkey 11951793
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath vmpm_pubs/190
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/92299
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/vmpm_pubs/190/1988_Roth_OpsoninDependent.pdf|||Fri Jan 14 21:51:23 UTC 2022
dc.subject.disciplines Veterinary Microbiology and Immunobiology
dc.subject.disciplines Veterinary Preventive Medicine, Epidemiology, and Public Health
dc.subject.disciplines Veterinary Toxicology and Pharmacology
dc.title Opsonin-dependent stimulation of bovine neutrophil oxidative metabolism by Brucella abortus
dc.type article
dc.type.genre article
dspace.entity.type Publication
relation.isAuthorOfPublication 909dd0b2-ec0a-41e2-b4e0-9e5ff76b7622
relation.isOrgUnitOfPublication 16f8e472-b1cd-4d8f-b016-09e96dbc4d83
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