Repetitive finger movement performance differs among Parkinson’s disease, Progressive Supranuclear Palsy, and spinocerebellar ataxia

dc.contributor.author Stegemoller, Elizabeth
dc.contributor.author Uzochukwu, Jennifer
dc.contributor.author Stegemoller, Elizabeth
dc.contributor.author Tillman, Mark
dc.contributor.author McFarland, Nikolaus
dc.contributor.author Subramony, SH
dc.contributor.author Okun, Michael
dc.contributor.author Hass, Chris
dc.contributor.department Kinesiology
dc.date 2018-02-19T02:26:37.000
dc.date.accessioned 2020-06-30T05:45:29Z
dc.date.available 2020-06-30T05:45:29Z
dc.date.copyright Thu Jan 01 00:00:00 UTC 2015
dc.date.issued 2015-01-01
dc.description.abstract <p><h3>Background</h3> <p id="x-x-x-x-Par1">Differentiating movement disorders is critical for appropriate treatment, prognosis, and for clinical trials. In clinical trials this is especially important as effects can be diluted by inclusion of inappropriately diagnosed participants. In early disease duration phases, disorders often have overlapping clinical features, such as impairments in repetitive finger movement, making diagnosis challenging. The purpose of this pilot study was to examine and compare repetitive finger movement performance in participants diagnosed with idiopathic Parkinson’s disease, Progressive Supranuclear Palsy, and spinocerebellar ataxias. <h3>Methods</h3> <p id="x-x-x-x-Par2">Participants completed an unconstrained index finger flexion/extension movement (i.e. finger tap) in time with an incremental acoustic tone. Measures of movement rate, movement amplitude, and coefficient of variation were compared among groups. <h3>Results</h3> <p id="x-x-x-x-Par3">Significant differences between groups were revealed for movement rate at faster tone rates. Participants with Parkinson’s disease tended to tap faster than the tone rate while participants with Progressive Supranuclear Palsy and spinocerebellar ataxia tended to tap slower. No significant differences were revealed for movement amplitude, but participants with spinocerebellar ataxia demonstrated greater variance in amplitude than participants with Parkinson’s disease. <h3>Conclusion</h3> <p id="x-x-x-x-Par4">Quantitative analysis of repetitive finger movement performance at faster rates may be helpful to differentiate Parkinson’s Disease, Progressive Supranuclear Palsy and spinocerebellar ataxia.</p>
dc.description.comments <p>This article is published as Stegemöller EL, Uzochukwu J, Tillman MD, McFarland NR, Subramony SH, Okun MS, Hass CJ. (2015) Repetitive finger movement performance differs among Parkinson’s disease, progressive supranuclear palsy, and spinocerebellar ataxia. J Clin Mov Dis, 2:6.</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/kin_pubs/22/
dc.identifier.articleid 1022
dc.identifier.contextkey 11049160
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath kin_pubs/22
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/52503
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/kin_pubs/22/RepetitiveFingerMovement.pdf|||Fri Jan 14 22:41:09 UTC 2022
dc.source.uri 10.1186/s40734-014-0015-y
dc.subject.disciplines Kinesiology
dc.subject.disciplines Motor Control
dc.subject.disciplines Neurology
dc.subject.disciplines Psychology of Movement
dc.subject.keywords Finger tapping
dc.subject.keywords movement disorders
dc.subject.keywords movement rate
dc.subject.keywords movement amplitude
dc.subject.keywords coefficient
dc.title Repetitive finger movement performance differs among Parkinson’s disease, Progressive Supranuclear Palsy, and spinocerebellar ataxia
dc.type article
dc.type.genre article
dspace.entity.type Publication
relation.isAuthorOfPublication 5fe1aec0-0d21-48d1-a2e2-a76303a1f482
relation.isOrgUnitOfPublication f7b0f2ca-8e43-4084-8a10-75f62e5199dd
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