Use of equine-origin antitoxins in piglets prior to exposure to mitigate the effects of Clostridium difficile infection – a pilot study

Date
2014-01-01
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Ramirez, Alejandro
Rowe, Eric
Arruda, Paulo
Ramirez, Alejandro
Madson, Darin
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Biomedical SciencesVeterinary Diagnostic and Production Animal Medicine
Abstract

Administration to newborn pigs of an oral or intraperitoneal dose of equine-origin Clostridium difficile antitoxin 4 hours before orogastric inoculation with a swine-origin C difficile field isolate resulted in lower histopathology scores 72 hours post challenge than in pigs receiving no antitoxin (P < .05).

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This article is published as Ramirez, Alejandro, Eric W. Rowe, Paulo H. Arruda, and Darin M. Madson. "Use of equine-origin antitoxins in piglets prior to exposure to mitigate the effects of Clostridium difficile infection–a pilot study." Journal of Swine Health and Production 22, no. 1 (2014): 29-32. Posted with permission.

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