Although one of the Clostridial. diseases of animals has been recognized as a distinct entity for 70 years, knowledge concerning disease caused by infections due to this genus of bacteria seems to have lagged somewhat as compared with some of the other bacterial diseases. The reason for this apparent lag is obvious. Symptoms and pathological lesions associated with Clostridial infections usually result from the effects of toxins which enter the blood stream. The fact that the actual site of infection is often quite remote from the site of greatest injury may, of course, be confusing to the investigator.