Extending the frontiers of mass spectrometric instrumentation and methods

Date
2010-01-01
Authors
Schieffer, Gregg
Major Professor
Advisor
R. S. Houk
Committee Member
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Altmetrics
Authors
Research Projects
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Chemistry
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Chemistry
Abstract

Ion mobility coupled to mass spectrometry is fast becoming a common tool to analyze biological systems. A novel ion trap — ion mobility — mass spectrometer was characterized primarily using ubiquitin, cytochrome c, and YbhB proteins. The time resolved protein ion heating between the ion trap and drift tube is described. Besides the novel instrument, mass spectrometric methods were developed for the rapid analysis of coal using direct analysis in real time.

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