Analyzing Chromosomes, Ion Channels and Novel Nucleic Acid Structures by AFM

Date
1994
Authors
Henderson, Eric
Ambrosio, Linda
Henderson, Eric
Mosher, Curtis
Jondle, Daniel
Stanley, Elis
Haydon, Philip
Marsh, Thomas
Vesenka, James
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Altmetrics
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Research Projects
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Zoology and Genetics
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Zoology and Genetics
Abstract

The atomic force microscope (AFM) is proving to be a powerful tool for analysis of biological samples. We provide three examples of the application of AFM to the study of biological questions. First, polytene chromosomes from Drosophila are imaged and manipulated by the AFM. Second, the localization of calcium channels on the release face of a nerve terminal is described. Finally, analyses of a new form of DNA, the G-wire, is presented. These examples illustrate the wide variety of biological questions to which AFM can contribute.

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This is a proceeding from NATO Advanced Research Workshop: "Scanning Probe Microscopies and Molecular Materials" (1994): 1.

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