The efficacy of bacterial vaccines to prevent respiratory diseases in swine: A protocol for a systematic review

dc.contributor.author O'Connor, Annette
dc.contributor.author Sargeant, Jan
dc.contributor.author Correia-Lima-Linhares, Daniel
dc.contributor.author Linhares, Daniel
dc.contributor.author Winder, Charlotte
dc.contributor.author O'Connor, Annette
dc.contributor.author O’Sullivan, Terri
dc.contributor.department Veterinary Diagnostic and Production Animal Medicine
dc.date 2018-09-04T03:20:43.000
dc.date.accessioned 2020-07-07T05:13:53Z
dc.date.available 2020-07-07T05:13:53Z
dc.date.copyright Mon Jan 01 00:00:00 UTC 2018
dc.date.embargo 2018-08-27
dc.date.issued 2018-01-01
dc.description.abstract <p>The treatment and prevention of infectious diseases in pigs is an important aspect of swine production worldwide. The prudent use of antimicrobials and other therapeutic drugs is a primary responsibility of swine producers and veterinarians and decisions surrounding the use of drug therapy include considerations such as cost, efficacy, and food safety. The World Health Organization has published numerous reports urging all stakeholders concerned with both food-producing animals and humans to establish recommended steps to enhance the prudent use of antimicrobials (WHO, 2015). Similarly, the Organization for Animal Health has also published recommendations and position statements regarding prudent use and risk management related to antimicrobial use in animals (OIE, 2017).</p> <p>Antibiotic therapy is used to treat and prevent respiratory diseases in pigs and there are numerous pathogenic organisms involved in all of the predominant swine respiratory diseases (Karriker, et al, 2012). In addition to antibiotics, vaccines targeted towards respiratory pathogens have been used extensively in swine production and are often used in combination with other approaches to reduce the incidence of disease. The usefulness of a vaccine or vaccine program varies from herd to herd and the complex interactions between host, agent and environment in swine production makes the design of a vaccine program challenging for veterinarians. There are many studies that have assessed the efficacy of antibiotics and vaccines for the treatment and prevention Mycoplasma hyopneumonia, for example, however, they often report conflicting results adding to the complexity of the decision-making process (Thacker and Minion, 2012).</p> <p>Understanding the efficacy of these vaccines products is essential to optimizing their use in order to decrease reliance on antibiotics for both treatment and prevention of swine respiratory disease. Systematic reviews of randomized controlled trials in these areas will yield the highest level of evidence for efficacy of treatment under field conditions (Sargeant and O’Connor, 2014). Although vaccines exist for both viral and bacterial causes of respiratory diseases of swine, and antibiotics often are used in the treatment of both, this review will focus on bacterial causes for logistical reasons.</p>
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dc.identifier archive/lib.dr.iastate.edu/vdpam_reports/17/
dc.identifier.articleid 1016
dc.identifier.contextkey 12730954
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath vdpam_reports/17
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/92139
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/vdpam_reports/17/2018_O_Connor_EfficacyBacterial.pdf|||Fri Jan 14 21:12:35 UTC 2022
dc.subject.disciplines Large or Food Animal and Equine Medicine
dc.subject.disciplines Veterinary Infectious Diseases
dc.subject.disciplines Veterinary Microbiology and Immunobiology
dc.title The efficacy of bacterial vaccines to prevent respiratory diseases in swine: A protocol for a systematic review
dc.type article
dc.type.genre report
dspace.entity.type Publication
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