Validity of predictive equations for 24-h urinary sodium excretion in adults aged 18–39 y1–5 Cogswell, Mary Wang, Chia-Yih Carriquiry, Alicia Chen, Te-Ching Pfeiffer, Christine Elliott, Paul Gillespie, Cathleen Carriquiry, Alicia Sempos, Christopher Liu, Kiang Perrine, Cria Swanson, Christine Caldwell, Kathleen Loria, Catherine
dc.contributor.department Statistics 2018-02-17T06:20:42.000 2020-07-02T06:57:37Z 2020-07-02T06:57:37Z 2013-01-01
dc.description.abstract <p>Background: Collecting a 24-h urine sample is recommended for monitoring the mean population sodium intake, but implementation can be difficult. Objective: The objective was to assess the validity of published equations by using spot urinary sodium concentrations to predict 24-h sodium excretion. Design: This was a cross-sectional study, conducted from June to August 2011 in metropolitan Washington, DC, of 407 adults aged 18–39 y, 48% black, who collected each urine void in a separate container for 24 h. Four timed voids (morning, afternoon, evening, and overnight) were selected from each 24-h collection. Published equations were used to predict 24-h sodium excretion with spot urine by specimen timing and race-sex subgroups. We examined mean differences with measured 24-h sodium excretion (bias) and individual differences with the use of Bland-Altman plots. Results: Across equations and specimens, mean bias in predicting 24-h sodium excretion for all participants ranged from2267 to 1300mg (Kawasaki equation). Bias was least with International Cooperative Study on Salt, Other Factors, and Blood Pressure (INTERSALT) equations with morning (2165 mg; 95% CI: 2295, 36 mg), afternoon (290 mg; 2208, 28 mg), and evening (2120 mg; 2230, 211 mg) specimens. With overnight specimens, mean bias was least when the Tanaka (223 mg; 95% CI: 2141, 95 mg) or Mage (2145 mg; 2314, 25 mg) equations were used but was statistically significant when using the Tanaka equations among females (216 to 243 mg) and the Mage equations among races other than black (2554 to 2372 mg). Significant over- and underprediction occurred across individual sodium excretion concentrations. Conclusions: Using a single spot urine, INTERSALT equations may provide the least biased information about population mean sodium intakes among young US adults. None of the equations evaluated provided unbiased estimates of individual 24-h sodium excretion. This trial was registered at as NCT01631240.</p>
dc.description.comments <p>This article is from <em>American Journal of Clinical Nutrition</em> 98 (2013): 1502, doi: <a href="" target="_blank">10.3945/ajcn.113.059436</a>.</p>
dc.format.mimetype application/pdf
dc.identifier archive/
dc.identifier.articleid 1030
dc.identifier.contextkey 7855335
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath stat_las_pubs/28
dc.language.iso en
dc.source.bitstream archive/|||Fri Jan 14 23:09:15 UTC 2022
dc.source.uri 10.3945/ajcn.113.059436
dc.subject.disciplines Public Health
dc.subject.disciplines Statistics and Probability
dc.subject.disciplines Urology
dc.subject.keywords international cooperative study on salt other factors and blood pressure equation
dc.subject.keywords kawasaki equation
dc.subject.keywords mage equation
dc.subject.keywords micturition
dc.subject.keywords sodium excretion
dc.subject.keywords tanaka equation
dc.subject.keywords urinalysis
dc.subject.keywords nutrition surveys
dc.title Validity of predictive equations for 24-h urinary sodium excretion in adults aged 18–39 y1–5
dc.type article
dc.type.genre article
dspace.entity.type Publication
relation.isAuthorOfPublication 6ddd5891-2ad0-4a93-89e5-8c35c28b0de4
relation.isOrgUnitOfPublication 264904d9-9e66-4169-8e11-034e537ddbca
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