Alterations in the Colonic Microbiota of Pigs Associated with Feeding Distillers Dried Grains with Solubles

dc.contributor.author Plummer, Paul
dc.contributor.author Burrough, Eric
dc.contributor.author Arruda, Bailey
dc.contributor.author Patience, John
dc.contributor.author Patience, John
dc.contributor.author Plummer, Paul
dc.contributor.department Animal Science
dc.contributor.department Veterinary Microbiology and Preventive Medicine
dc.contributor.department Veterinary Diagnostic and Production Animal Medicine
dc.date 2018-02-19T05:28:03.000
dc.date.accessioned 2020-07-07T05:13:46Z
dc.date.available 2020-07-07T05:13:46Z
dc.date.copyright Thu Jan 01 00:00:00 UTC 2015
dc.date.issued 2015-11-10
dc.description.abstract <p>In an effort to reduce feed costs, many pork producers have increased their use of coproducts of biofuel production in commercial pig diets, including increased feeding of distiller’s dried grains with solubles (DDGS). The inclusion of DDGS increases the insoluble fiber content in the ration, which has the potential to impact the colonic microbiota considerably as the large intestine contains a dynamic microenvironment with tremendous interplay between microorganisms. Any alteration to the physical or chemical properties of the colonic contents has the potential to impact the resident bacterial population and potentially favor or inhibit the establishment of pathogenic species. In the present study, colonic contents collected at necropsy from pigs fed either 30% or no DDGS were analyzed to examine the relative abundance of bacterial taxa associated with feeding this ingredient. No difference in alpha diversity (richness) was detected between diet groups. However, the beta diversity was significantly different between groups with feeding of DDGS being associated with a decreased Firmicutes:Bacteriodetes ratio (<em>P</em> = .004) and a significantly lower abundance of <em>Lactobacillus</em> spp. (<em>P</em> = .016). Predictive functional profiling of the microbiota revealed more predicted genes associated with carbohydrate metabolism, protein digestion, and degradation of glycans in the microbiota of pigs fed DDGS. Taken together, these findings confirm that alterations in dietary insoluble fiber significantly alter the colonic microbial profile of pigs and suggest the resultant microbiome may predispose to the development of colitis.</p>
dc.description.comments <p>This article is published as Burrough ER, Arruda BL, Patience JF, Plummer PJ (2015) Alterations in the Colonic Microbiota of Pigs Associated with Feeding Distillers Dried Grains with Solubles. PLoS ONE 10(11): e0141337. doi: <a href="https://doi.org/10.1371/journal.pone.0141337">10.1371/journal.pone.0141337</a>. Posted with permission.</p>
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dc.identifier archive/lib.dr.iastate.edu/vdpam_pubs/93/
dc.identifier.articleid 1092
dc.identifier.contextkey 11172346
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath vdpam_pubs/93
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/92124
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/vdpam_pubs/93/2015_Plummer_AltercationsColonic.PDF|||Sat Jan 15 02:31:18 UTC 2022
dc.source.uri 10.1371/journal.pone.0141337
dc.subject.disciplines Animal Sciences
dc.subject.disciplines Large or Food Animal and Equine Medicine
dc.subject.disciplines Veterinary Microbiology and Immunobiology
dc.subject.disciplines Veterinary Preventive Medicine, Epidemiology, and Public Health
dc.title Alterations in the Colonic Microbiota of Pigs Associated with Feeding Distillers Dried Grains with Solubles
dc.type article
dc.type.genre article
dspace.entity.type Publication
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