Astrovirus Infection in Hatchling Turkeys: Histologic, Morphometric, and Ultrastructural Findings Thouvenelle, Mari Haynes, Joseph Haynes, Joseph Reynolds, Don
dc.contributor.department Veterinary Pathology 2018-02-18T23:33:35.000 2020-07-07T05:16:12Z 2020-07-07T05:16:12Z Sun Jan 01 00:00:00 UTC 1995 1995
dc.description.abstract <p>In three separate experiments, 2- or 5-day-old commercial turkey poults were inoculated orally with astrovirus and examined for clinical signs and for gross and microscopic lesions over a period of 14 days. By day 2 postinoculation (PI), inoculated poults had de- veloped diarrhea, generalized loss of intestinal tone, and dilated ceca that contained light- yellow fluid feces and gas; these changes persisted through day 10 PI. Mild crypt hyperplasia was the only change discernible by light microscopy, and it was first noted in the proximal jejunum on day 1 PI, in the distal jejunum and ileum on day 3 PI, and in the duodenum on day 5 PI. A significant (P < 0.05) increase in crypt depth and area was documented by image analysis on day 3 PI. Ultrastructural evaluation revealed intracytoplasmic aggregates of astro- virus in enterocytes on the sides and base of villi in the ileum and distal jejunum on day 3 PI. Based on the findings, it was concluded that astrovirus caused lesions and replicated in both upper and lower segments of the small intestine in turkey poults.</p>
dc.description.comments <p>This article is published as Thouvenelle, Mari L., Joseph S. Haynes, and Don L. Reynolds. "Astrovirus infection in hatchling turkeys: histologic, morphometric, and ultrastructural findings." Avian diseases (1995): 328-336. doi: <a href="" target="_blank">10.2307/1591875</a>. Posted with permission.</p>
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dc.identifier.articleid 1091
dc.identifier.contextkey 10861159
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath vpath_pubs/88
dc.language.iso en
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dc.source.uri 10.2307/1591875
dc.subject.disciplines Poultry or Avian Science
dc.subject.disciplines Veterinary Microbiology and Immunobiology
dc.subject.disciplines Veterinary Pathology and Pathobiology
dc.subject.disciplines Veterinary Toxicology and Pharmacology
dc.title Astrovirus Infection in Hatchling Turkeys: Histologic, Morphometric, and Ultrastructural Findings
dc.type article
dc.type.genre article
dspace.entity.type Publication
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