Extension of electrical engineering to bioengineering topics: magnetic fermentation and microfluidic nematode assays

dc.contributor.advisor Santosh Pandey
dc.contributor.author Deutmeyer, Alex
dc.contributor.department Electrical and Computer Engineering
dc.date 2018-08-12T03:17:15.000
dc.date.accessioned 2020-06-30T02:31:11Z
dc.date.available 2020-06-30T02:31:11Z
dc.date.copyright Thu Jan 01 00:00:00 UTC 2009
dc.date.embargo 2013-06-05
dc.date.issued 2009-01-01
dc.description.abstract <p>The Department of Electrical and Computer Engineering (ECpE) at Iowa State University added bioengineering to the department's list of strategic research areas in 2006. In an effort to foster a bioengineering center of excellence within the department and to promote multidisciplinary research, two bioengineering research projects were performed: magnetic fermentation and microfluidic nematode assay development. The background of these research topics, the work completed for each, and their future prospects are discussed in this thesis.</p> <p>Fuel ethanol produced through fermentation has recently received attention during the search for eco-friendly, renewable energy sources. Previous research has been completed to observe the effects of magnetic fermentation but conflicting results have been reported. Research was performed to characterize the fermentation kinetics of S. Cerevisiae ATCCy 24859 at cell concentration loading rates from 102 to 107 CFU/mL and to determine the effects of magnetic field enhanced fermentation on cell growth and ethanol production. It was found that magnetic fields have no statistically significant affect on cell growth. Non-homogeneous static magnetic fields of 220 mT caused a 9% ethanol concentration peak enhancement over the control group for 2% dextrose loading experiments and a peak ethanol concentration six hours before the control group for 6% dextrose loading experiments.</p> <p>Non-parasitic nematodes are common research subjects, but the characterization of parasitic nematodes has been limited by the versatility and resolution of available technology. A high resolution microfluidic assay for the measurement of parasitic nematodes' undulatory locomotive parameters was developed and tested. A characterization and comparison of these parameters for H. glycines and two isolates of O. dentatum revealed that a correlation between nematodes' undulatory parameters and their physiological state exists, suggesting prospects for new nematode migration and drug chemotaxis assays.</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/etd/10812/
dc.identifier.articleid 1839
dc.identifier.contextkey 2807037
dc.identifier.doi https://doi.org/10.31274/etd-180810-1882
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath etd/10812
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/25018
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/etd/10812/Deutmeyer_iastate_0097M_10660.pdf|||Fri Jan 14 18:28:50 UTC 2022
dc.subject.disciplines Electrical and Computer Engineering
dc.subject.keywords Fermentation
dc.subject.keywords Microfluidics
dc.subject.keywords Nematology
dc.subject.keywords Parasitology
dc.subject.keywords Renewable energy
dc.title Extension of electrical engineering to bioengineering topics: magnetic fermentation and microfluidic nematode assays
dc.type article
dc.type.genre thesis
dspace.entity.type Publication
relation.isOrgUnitOfPublication a75a044c-d11e-44cd-af4f-dab1d83339ff
thesis.degree.level thesis
thesis.degree.name Master of Science
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