Triacetic acid lactone as a common intermediate for the synthesis of 4-hydroxy-2-pyridones and 4-amino-2-pyrones

Date
2015-12-01
Authors
Kraus, George
Wanninayake, Umayangani
Bottoms, Jashaun
Journal Title
Journal ISSN
Volume Title
Publisher
Altmetrics
Authors
Research Projects
Organizational Units
Chemistry
Organizational Unit
Journal Issue
Series
Abstract

At ambient temperature, triacetic acid lactone reacts with amines to produce 4-amino-2-pyrones. If the temperature is raised to 100 °C, 4-hydroxy-2-pyridones are generated.

Description

This is a manuscript of an article published as Kraus, George A., Umayangani K. Wanninayake, and Jashaun Bottoms. "Triacetic acid lactone as a common intermediate for the synthesis of 4-hydroxy-2-pyridones and 4-amino-2-pyrones." Tetrahedron Letters 57, no. 11 (2016): 1293-1295. 10.1016/j.tetlet.2016.02.043. Posted with permission.

Keywords
2-pyrone, Triacetic acid lactone, Amine, 4-amino-2-pyrones, 4-hydroxy-2-pyridones
Citation
DOI
Collections