Miniaturized chemical sensors for physiological monitoring in space exploration

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dc.contributor.advisor Mary Helen Greer
dc.contributor.advisor Dennis C. Johnson
dc.contributor.author Coldiron, Shelley
dc.contributor.department Chemical and Biological Engineering
dc.date 2018-08-22T23:21:45.000
dc.date.accessioned 2020-06-30T07:03:04Z
dc.date.available 2020-06-30T07:03:04Z
dc.date.copyright Fri Jan 01 00:00:00 UTC 1993
dc.date.issued 1993
dc.description.abstract <p>This thesis describes the development of a dual-beam, fiber optic instrument for solution-phase analysis of thin-film sensors. Colorimetric indicators are described for incorporation into porous polymeric films. The films are immobilized at the distal ends of optical fibers and yield an optical response proportional to the target analyte. In its present form, the instrument functions in an absorbance mode as a solid-state, dual-wavelength photometer and is equipped with a custom-designed microprocessor controller and data processor. The described study encompasses interdisciplinary research in the fields of biomedical engineering, synthetic organic chemistry, interfacial chemistry, materials science, and computer and electrical engineering;The primary emphasis in development of thin-film sensors focused on pH. Other indicators are proposed for detecting calcium, potassium, and sodium. These ions are major physiological indicators of homeostasis; therefore, monitoring of these parameters is important in determining the clinical status of astronauts on long-term space missions.</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/rtd/10221/
dc.identifier.articleid 11220
dc.identifier.contextkey 6386172
dc.identifier.doi https://doi.org/10.31274/rtd-180813-9598
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath rtd/10221
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/63344
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/rtd/10221/r_9334970.pdf|||Fri Jan 14 18:16:33 UTC 2022
dc.subject.disciplines Analytical Chemistry
dc.subject.disciplines Biomedical Engineering and Bioengineering
dc.subject.keywords Biomedical engineering
dc.title Miniaturized chemical sensors for physiological monitoring in space exploration
dc.type article
dc.type.genre dissertation
dspace.entity.type Publication
relation.isOrgUnitOfPublication 86545861-382c-4c15-8c52-eb8e9afe6b75
thesis.degree.level dissertation
thesis.degree.name Doctor of Philosophy
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