Cloning of the Pig Counterpart of a Gene Involved in Resistance to Bacterial Infection Tuggle, Christopher Schmitz, Claire Gingerich-Feil, Diane 2018-02-13T00:38:06.000 2020-07-02T06:59:44Z 2020-07-02T06:59:44Z Wed Jan 01 00:00:00 UTC 1997 2012-08-20 1997
dc.description.abstract <p>The pig gene corresponding to a mouse protein known to cause susceptibility to infection by several different bacteria (NRAMP1) was cloned and the entire protein coding region sequenced. The pig protein encoded within this gene is highly similar to the mouse and human NRAMP1. A preliminary expression profile of pig NRAMP1 indicates it is expressed in spleen, a rich source of immune cells, and may be expressed in other tissues at low levels. Taken together, these data strongly indicate that the newly cloned gene has a similar physiological function in pigs to that seen for mouse NRAMP1. With this new information, the association of NRAMP1 to Salmonella infection in pigs can be tested.</p>
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dc.identifier archive/
dc.identifier.articleid 1018
dc.identifier.contextkey 3236138
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath swinereports_1996/19
dc.language.iso en
dc.relation.ispartofseries Animal Science Research Reports
dc.source.bitstream archive/|||Fri Jan 14 21:48:27 UTC 2022
dc.subject.disciplines Agriculture
dc.subject.disciplines Animal Sciences
dc.subject.keywords ASL R1382
dc.title Cloning of the Pig Counterpart of a Gene Involved in Resistance to Bacterial Infection
dc.type article
dc.type.genre breeding_physiology
dspace.entity.type Publication
relation.isSeriesOfPublication 7f3839b7-b833-4418-a6fa-adda2b23950a
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