Adaptive resistance to Biocides and implications of cross-resistance to Antimicrobial Agents in Foodborne Pathogens.
This study was focused on the potential for adaptive resistance in Salmonella and Escherichia coli to commonly used biocides, to identify resistance strategies and any cross-resistance to antibiotics. Bacteria were serially exposed in sub-inhibitory concentrations of biocides and adaptive resistance was observed in all strains investigated. Erythromycin-resistant Salm. Enteritidis did not cross-resist to biocides, whereas erythromycin-resistant Salm. Typhimurium express cross-resistance to chlorohexidine. Benzalkonium chloride-resistant Salm. Virchow showed an elevated resistance to chlorohexidine, however chlorohexidine-resistant Salm. Virchow did not demonstrate it back.