Effects of Dietary Cholesterol and Its Oxidation Products on Pathological Lesions and Cholesterol and Lipid Oxidation in the Rabbit Liver

dc.contributor.author Hur, Sun Jin
dc.contributor.author Nam, Ki Chang
dc.contributor.author Ahn, Dong
dc.contributor.author Min, Byongrok
dc.contributor.author Du, Min
dc.contributor.author Seo, Kwon Il
dc.contributor.author Ahn, Dong
dc.contributor.department Animal Science
dc.date 2018-02-16T04:47:44.000
dc.date.accessioned 2020-06-29T23:41:43Z
dc.date.available 2020-06-29T23:41:43Z
dc.date.copyright Wed Jan 01 00:00:00 UTC 2014
dc.date.issued 2014-01-01
dc.description.abstract <p>This study was conducted to determine the effects of dietary cholesterol (CHO) and cholesterol oxidation products (COPs) on the induction of pathological lesions in rabbit liver tissues. Liver lesions were induced only when the levels of CHO and COPs in the diet were very high. The amount of CHO measured in the liver increased when dietary CHO was increased; by comparison, dietary COPs affected liver CHO amounts to a lesser extent. The TBARS (thiobarbituric acid reactive substances) value measured for the liver samples also increased when dietary CHO and COP levels were elevated, and the TBARS value was more strongly affected by the amount of COPs in the diet than by the amount of CHO. At 6 and 12 weeks, COP levels were the highest in the group that received 1.2 g CHO + 0.8 g COPs, followed by the 0.5 g CHO + 0.5 g COPs and 1.6 g CHO + 0.4 g COPs groups; the control (0 g) group showed the lowest COP levels among all groups. In this study, we found that not only dietary CHO but also COPs were involved in hypercholesterolemia induced liver lesions when the amount of CHO and COPs was high.</p>
dc.description.comments <p>This article is from <em>BioMed Research International</em> 2014 (2014): 598612, doi:<a href="http://dx.doi.org/10.1155/2014/598612" target="_blank">10.1155/2014/598612</a>. Posted with permission</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/ans_pubs/65/
dc.identifier.articleid 1062
dc.identifier.contextkey 6979841
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath ans_pubs/65
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/9991
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/ans_pubs/65/2014_Hur_EffectsDietary.pdf|||Sat Jan 15 01:23:29 UTC 2022
dc.source.uri 10.1155/2014/598612
dc.subject.disciplines Agriculture
dc.subject.disciplines Animal Sciences
dc.subject.disciplines Meat Science
dc.title Effects of Dietary Cholesterol and Its Oxidation Products on Pathological Lesions and Cholesterol and Lipid Oxidation in the Rabbit Liver
dc.type article
dc.type.genre article
dspace.entity.type Publication
relation.isAuthorOfPublication d3386101-2f0d-4375-ab44-ac1addb6a9ad
relation.isOrgUnitOfPublication 85ecce08-311a-441b-9c4d-ee2a3569506f
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