Genetic Basis of Resistance to Avian Influenza Drobik-Czwarno, Wioleta Wolc, Anna Fulton, Janet Arango, Jesus Settar, Petek Wolc, Anna Dekkers, Jack 2018-08-25T18:54:43.000 2020-06-29T23:37:06Z 2020-06-29T23:37:06Z Sun Jan 01 00:00:00 UTC 2017 2017-01-01
dc.description.abstract <p>Two high pathogenic avian influenza (HPAI) outbreaks haveseverelyaffected the poultry industryon the American continentwithin the last four years; a 2012 H7N3 outbreak in Mexicoand a 2015 H5N2 outbreak in the US. Blood samples were collectedfrom survivors of each outbreak plus age and genetics matched non-affected controls. As surviving birds could contain natural genetic mutation(s) that make them resistant to HPAI,the goal of the present study was to identify genomic regions associated with resistance to HPAIand to determinewhether resistance regionsare the same fordifferent virus strains.Four genomic regions were identified for the H5N2 outbreak and fivedifferent regions were identified for the H7N3 outbreak. The apparentdifferent genomic regions of resistance for different virus strains is achallengefor the poultry industry, as it requires amore diversified strategyfor improving resistance toAI.</p>
dc.identifier archive/
dc.identifier.articleid 2283
dc.identifier.contextkey 9913265
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath ans_air/vol663/iss1/43
dc.language.iso en
dc.relation.ispartofseries Animal Science Research Reports
dc.relation.ispartofseries ASL R3170
dc.source.bitstream archive/|||Sat Jan 15 00:15:06 UTC 2022
dc.subject.disciplines Animal Diseases
dc.subject.disciplines Genetics
dc.subject.disciplines Poultry or Avian Science
dc.title Genetic Basis of Resistance to Avian Influenza
dc.type article
dc.type.genre poultry
dspace.entity.type Publication
relation.isAuthorOfPublication 7103f024-4508-422f-82ff-1d5e544596a2
relation.isJournalIssueOfPublication d617d232-28f0-4f88-964e-6cae4e0f2321
relation.isSeriesOfPublication 7f3839b7-b833-4418-a6fa-adda2b23950a
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