Genetic Basis of Resistance to Avian Influenza

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dc.contributor.author Drobik-Czwarno, Wioleta
dc.contributor.author Wolc, Anna
dc.contributor.author Fulton, Janet
dc.contributor.author Arango, Jesus
dc.contributor.author Settar, Petek
dc.contributor.author Wolc, Anna
dc.contributor.author Dekkers, Jack
dc.date 2018-08-25T18:54:43.000
dc.date.accessioned 2020-06-29T23:37:06Z
dc.date.available 2020-06-29T23:37:06Z
dc.date.copyright Sun Jan 01 00:00:00 UTC 2017
dc.date.issued 2017-01-01
dc.description.abstract <p>Two high pathogenic avian influenza (HPAI) outbreaks haveseverelyaffected the poultry industryon the American continentwithin the last four years; a 2012 H7N3 outbreak in Mexicoand a 2015 H5N2 outbreak in the US. Blood samples were collectedfrom survivors of each outbreak plus age and genetics matched non-affected controls. As surviving birds could contain natural genetic mutation(s) that make them resistant to HPAI,the goal of the present study was to identify genomic regions associated with resistance to HPAIand to determinewhether resistance regionsare the same fordifferent virus strains.Four genomic regions were identified for the H5N2 outbreak and fivedifferent regions were identified for the H7N3 outbreak. The apparentdifferent genomic regions of resistance for different virus strains is achallengefor the poultry industry, as it requires amore diversified strategyfor improving resistance toAI.</p>
dc.identifier archive/lib.dr.iastate.edu/ans_air/vol663/iss1/43/
dc.identifier.articleid 2283
dc.identifier.contextkey 9913265
dc.identifier.doi https://doi.org/10.31274/ans_air-180814-341
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath ans_air/vol663/iss1/43
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/9343
dc.language.iso en
dc.relation.ispartofseries Animal Science Research Reports
dc.relation.ispartofseries ASL R3170
dc.source.bitstream archive/lib.dr.iastate.edu/ans_air/vol663/iss1/43/R3170.pdf|||Sat Jan 15 00:15:06 UTC 2022
dc.subject.disciplines Animal Diseases
dc.subject.disciplines Genetics
dc.subject.disciplines Poultry or Avian Science
dc.title Genetic Basis of Resistance to Avian Influenza
dc.type article
dc.type.genre poultry
dspace.entity.type Publication
relation.isAuthorOfPublication 7103f024-4508-422f-82ff-1d5e544596a2
relation.isJournalIssueOfPublication d617d232-28f0-4f88-964e-6cae4e0f2321
relation.isSeriesOfPublication 7f3839b7-b833-4418-a6fa-adda2b23950a
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