Compatibility of matrix-assisted laser desorption/ionization- mass spectrometry imaging with porous fingerprint development techniques

dc.contributor.advisor Young-Jin Lee
dc.contributor.author King, Emily
dc.contributor.department Chemistry
dc.date 2020-06-26T20:01:32.000
dc.date.accessioned 2020-06-30T03:22:23Z
dc.date.available 2020-06-30T03:22:23Z
dc.date.copyright Fri May 01 00:00:00 UTC 2020
dc.date.embargo 2020-06-23
dc.date.issued 2020-01-01
dc.description.abstract <p>This thesis encompasses work done to aid in the incorporation of matrix-assisted laser desorption/ionization - mass spectrometry imaging (MALDI-MSI) into the forensic workflow. MALDI-MSI is a valuable technique in that chemical information, in addition to the location of the compounds, can be obtained. In the first chapter, an introduction to the technique and its applications and benefits for the field of forensics are presented. The following chapter details a set of experiments comparing MALDI-MSI with porous surface fingerprint development techniques, specifically ninhydrin and iodine-fuming. It was determined that MALDI-MSI is compatible with both techniques and able to reveal chemical information from a fingerprint. The MS image quality was also compared, and iodine-fumed fingerprints showed analogous images to the non-developed fingerprint, while ninhydrin-developed fingerprints seldom did. With iodine-fumed fingerprints maintaining ridge detail, further information can be determined, such as the deconvolution of the fingerprint and the surface surrounding the fingerprint. The final chapter concludes with an outlook on future directions of research related to this work.</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/etd/18001/
dc.identifier.articleid 9008
dc.identifier.contextkey 18242629
dc.identifier.doi https://doi.org/10.31274/etd-20200624-180
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath etd/18001
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/32184
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/etd/18001/King_iastate_0097M_18788.pdf|||Fri Jan 14 21:35:27 UTC 2022
dc.subject.keywords Forensic Science
dc.subject.keywords Iodine Fuming
dc.subject.keywords Latent Fingerprints
dc.subject.keywords Mass Spectrometry Imaging
dc.subject.keywords Matrix-Assisted Laser Desorption/Ionization
dc.subject.keywords Ninhydrin
dc.title Compatibility of matrix-assisted laser desorption/ionization- mass spectrometry imaging with porous fingerprint development techniques
dc.type article
dc.type.genre thesis
dspace.entity.type Publication
relation.isOrgUnitOfPublication 42864f6e-7a3d-4be3-8b5a-0ae3c3830a11
thesis.degree.discipline Analytical Chemistry
thesis.degree.level thesis
thesis.degree.name Master of Science
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